Literature DB >> 3440459

Effect of BMY-28100, a new cephalosporin, on Staphylococcus aureus nasal carriage.

R L Atmar1, M L Allen, J Freiman, C Kiefe, S Ehrman, S B Greenberg.   

Abstract

In order to examine the in vivo activity of BMY-28100, serial quantitative nasal cultures were taken from 52 nasal carriers of Staphylococcus aureus following administration of the antimicrobial. Nasal carriage rates and mean log titers decreased significantly during (days 2-4 and 5-8) and following (days 1-2 and 6-7) treatment. No change in antibiotic sensitivities was noted in follow-up isolates, and the MIC90 remained at 2mcg/ml. BMY-28100 demonstrated good in vivo activity against Staphylococcus aureus.

Entities:  

Mesh:

Substances:

Year:  1987        PMID: 3440459     DOI: 10.1007/BF02013070

Source DB:  PubMed          Journal:  Eur J Clin Microbiol        ISSN: 0722-2211            Impact factor:   3.267


  8 in total

1.  PERSON-TO-PERSON TRANSMISSION OF STAPHYLOCOCCUS AUREUS. QUANTITATIVE CHARACTERIZATION OF NASAL CARRIERS SPREADING INFECTION.

Authors:  N J EHRENKRANZ
Journal:  N Engl J Med       Date:  1964-07-30       Impact factor: 91.245

2.  THE USE OF GENTAMICIN AS A NASAL OINTMENT.

Authors:  A WHITE
Journal:  Am J Med Sci       Date:  1964-07       Impact factor: 2.378

3.  Healthy carriage of Staphylococcus aureus: its prevalence and importance.

Authors:  R E WILLIAMS
Journal:  Bacteriol Rev       Date:  1963-03

4.  Studies on the origin of drug-resistant staphylococci in a mental hospital.

Authors:  A WHITE; T HEMMERLY; M P MARTIN; V KNIGHT
Journal:  Am J Med       Date:  1959-07       Impact factor: 4.965

5.  The reacquisition of staphylococci by treated carriers: a demonstration of bacterial interference.

Authors:  R R Martin; A White
Journal:  J Lab Clin Med       Date:  1968-05

6.  In vivo effects of josamycin, erythromycin, and placebo therapy on nasal carriage of Staphylococcus aureus.

Authors:  S Z Wilson; R R Martin; M Putman
Journal:  Antimicrob Agents Chemother       Date:  1977-03       Impact factor: 5.191

7.  Quantitative nasal culture: a tool in antibiotic research.

Authors:  R R Martin; A White
Journal:  Appl Microbiol       Date:  1971-09

8.  Quantitative nasal cultures from carriers of Staphylococcus aureus: effects of oral therapy with erythromycin, rosamicin, and placebo.

Authors:  S Z Wilson; R R Martin; M Putman; S B Greenberg; R J Wallace; J G Jemsek
Journal:  Antimicrob Agents Chemother       Date:  1979-03       Impact factor: 5.191

  8 in total
  1 in total

1.  Immediate and long-term efficacy of systemic antibiotics for eradicating nasal colonization with Staphylococcus aureus.

Authors:  B A Lipsky; R E Pecoraro; J H Ahroni; R L Peugeot
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1992-01       Impact factor: 3.267

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.