Literature DB >> 34399100

Adolescent cortisol and DHEA responses to stress as prospective predictors of emotional and behavioral difficulties: A person-centered approach.

Jason José Bendezú1, Mariann Howland2, Michelle Thai3, Kristine Marceau4, Elizabeth A Shirtcliff5, Paul D Hastings6, Carolyn Zahn-Waxler7, Bonnie Klimes-Dougan3.   

Abstract

BACKGROUND: Well-orchestrated cortisol and DHEA stress responsivity is thought to support efficacious stressor management (i.e., coping) and reduce risk for psychopathology during adolescence. Evidence of these relations, however, is lacking empirically. This longitudinal investigation had three aims: 1) to identify within-adolescent profiles of joint cortisol-DHEA responsivity, 2) examine profiles as prospective predictors of adolescents' later emotional and behavioral difficulties, and 3) examine whether distraction coping helped buffer such prospective risk in each profile.
METHOD: At Time 1, boys (n = 110) and girls (n = 105) between 11 and 16 years of age with varied levels of risk for psychopathology completed a lab-based socio-evaluative stressor and questionnaires (e.g., coping, internalizing and externalizing problems). Emotional and behavioral adjustment was assessed again at Time 2 (2 years later).
RESULTS: Multi-trajectory modeling of adolescents' cortisol and DHEA within the context of the stressor revealed three groups: Normative (n = 107; 49.8%), Hyperresponsive (n = 64; 29.8%), Hyporesponsive (n = 44; 20.5%). Relative to Normative, Hyperresponsive and Hyporesponsive adolescents were more and less advanced in pubertal status, respectively. Hyperresponsive adolescents, but not Hyporesponsive, reported greater emotional and behavioral problems at Time 2, relative to Normative adolescents. Links between distraction coping and Time 2 adjustment varied across the groups. Specifically, distraction coping was associated with fewer Time 2 emotional and behavioral problems for Normative adolescents. However, the converse was true for Hyporesponsive adolescents, with distraction associated with greater Time 2 emotional and behavioral problems. Distraction was not associated with Time 2 emotional and behavioral problems for Hyperresponsive adolescents (i.e., elevated levels irrespective of distraction coping utilization).
CONCLUSION: Our results strengthen inference about the role neuroendocrine coordination plays in risk for psychopathology. Findings also help to clarify inconsistent distraction coping-psychopathology linkages, illustrating different patterns of cortisol-DHEA responsivity that support as well as thwart the use of this potentially efficacious strategy.
Copyright © 2021. Published by Elsevier Ltd.

Entities:  

Keywords:  Adolescence; Coping; Cortisol; DHEA; Externalizing; Internalizing

Mesh:

Substances:

Year:  2021        PMID: 34399100      PMCID: PMC8932361          DOI: 10.1016/j.psyneuen.2021.105365

Source DB:  PubMed          Journal:  Psychoneuroendocrinology        ISSN: 0306-4530            Impact factor:   4.693


  37 in total

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2.  The anterior attention network: associations with temperament and neuroendocrine activity in 6-year-old children.

Authors:  Elysia Poggi Davis; Jacqueline Bruce; Megan R Gunnar
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3.  Hormones: commentary. Riding the physiological roller coaster: adaptive significance of cortisol stress reactivity to social contexts.

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4.  Adrenocortical activity in at-risk and normally developing adolescents: individual differences in salivary cortisol basal levels, diurnal variation, and responses to social challenges.

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7.  What constitutes effective coping and efficient physiologic regulation following psychosocial stress depends on involuntary stress responses.

Authors:  Jason J Bendezú; E D Perzow Sarah; E Wadsworth Martha
Journal:  Psychoneuroendocrinology       Date:  2016-07-06       Impact factor: 4.905

Review 8.  Regulation of the adrenal androgen biosynthesis.

Authors:  William E Rainey; Yasuhiro Nakamura
Journal:  J Steroid Biochem Mol Biol       Date:  2007-09-11       Impact factor: 4.292

9.  Salivary dehydroepiandrosterone responsiveness to social challenge in adolescents with internalizing problems.

Authors:  Elizabeth Shirtcliff; Carolyn Zahn-Waxler; Bonnie Klimes-Dougan; Marcia Slattery
Journal:  J Child Psychol Psychiatry       Date:  2007-06       Impact factor: 8.982

10.  Rumination, anxiety, depressive symptoms and subsequent depression in adolescents at risk for psychopathology: a longitudinal cohort study.

Authors:  Paul O Wilkinson; Tim J Croudace; Ian M Goodyer
Journal:  BMC Psychiatry       Date:  2013-10-08       Impact factor: 3.630

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1.  Exploring joint HPA-inflammatory stress response profiles in adolescent girls: Implications for developmental models of neuroendocrine dysregulation.

Authors:  Jason José Bendezú; Casey D Calhoun; Meghan Vinograd; Megan W Patterson; Karen D Rudolph; Matteo Giletta; Paul Hastings; Matthew K Nock; George M Slavich; Mitchell J Prinstein
Journal:  Dev Psychobiol       Date:  2022-03       Impact factor: 3.038

2.  Psychobiological foundations of coping and emotion regulation: Links to maltreatment and depression in a racially diverse, economically disadvantaged sample of adolescent girls.

Authors:  Jason José Bendezú; Elizabeth D Handley; Jody T Manly; Sheree L Toth; Dante Cicchetti
Journal:  Psychoneuroendocrinology       Date:  2022-06-08       Impact factor: 4.693

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