Literature DB >> 34396135

Paraspinal desmoid fibromatosis after lumbar epidural analgesia.

E Remedios1, D Sommerfield2,3, W Fellingham2, N Powers4, K Stannage5, J W S Hii1,6.   

Abstract

A 14-year-old girl with cerebral palsy presented for bilateral lower limb surgery for spasticity. A lumbar epidural catheter was sited under general anaesthesia on the third attempt and used intra-operatively with good effect. A local anaesthetic infusion was used for postoperative analgesia but was noted to be leaking under the dressing with a patchy, unilateral block. The catheter was therefore removed on the second postoperative day. Following discharge, the patient progressively developed new back and leg pain for which she was re-admitted seven weeks later. This was investigated and initially thought to be myositis of the erector spinae muscles on magnetic resonance imaging. When the patient failed to respond to treatment, a muscle biopsy demonstrated desmoid fibromatosis. Trauma may cause or accelerate the development of desmoid fibromatosis, which has also been theorised to arise from scar tissue in previously injured areas. We hypothesise that challenging epidural placement or the leakage of the local anaesthetic agent into the surrounding muscular tissue, inducing local myonecrosis, could have been the triggering or accelerating event in tumour development. This may be the first reported case of extra-abdominal desmoid fibromatosis in association with epidural placement.
© 2021 Association of Anaesthetists.

Entities:  

Keywords:  analgesia; epidural; fibroma; magnetic resonance imaging; paraspinal muscles

Year:  2021        PMID: 34396135      PMCID: PMC8340928          DOI: 10.1002/anr3.12129

Source DB:  PubMed          Journal:  Anaesth Rep        ISSN: 2637-3726


  8 in total

1.  Local anaesthetic-induced myotoxicity in regional anaesthesia: a systematic review and empirical analysis.

Authors:  N Hussain; C J L McCartney; J M Neal; J Chippor; L Banfield; F W Abdallah
Journal:  Br J Anaesth       Date:  2018-08-08       Impact factor: 9.166

Review 2.  The management of desmoid tumours: A joint global consensus-based guideline approach for adult and paediatric patients.

Authors: 
Journal:  Eur J Cancer       Date:  2020-01-28       Impact factor: 9.162

3.  Pediatric recurrent aggressive spinal fibromatosis with progressive kyphosis and neurological deficits.

Authors:  B Yogesh Kumar; S Vidyadhara; B M Vadhiraja
Journal:  J Orthop Surg (Hong Kong)       Date:  2019 May-Aug       Impact factor: 1.118

Review 4.  Extra-abdominal desmoid fibromatosis: A review of management, current guidance and unanswered questions.

Authors:  N Eastley; T McCulloch; C Esler; I Hennig; J Fairbairn; A Gronchi; R Ashford
Journal:  Eur J Surg Oncol       Date:  2016-02-19       Impact factor: 4.424

5.  Multifocal occurrence of extra-abdominal desmoid type fibromatosis - A rare manifestation. A clinicopathological study of 6 sporadic cases and 1 hereditary case.

Authors:  Elise M Bekers; Danique L M van Broekhoven; Thijs van Dalen; Johan J Bonenkamp; Ingrid C M van der Geest; Jacky W J de Rooy; Joost M van Gorp; David H Creytens; Wendy W J de Leng; Blanca Scheijen; Astrid Eijkelenboom; Uta Flucke
Journal:  Ann Diagn Pathol       Date:  2018-04-21       Impact factor: 2.090

Review 6.  Spinal fibromatosis: a report of two cases and review of the literature.

Authors:  Sophia F Shakur; Ippei Takagi; Jamie A Jacobsohn; Barbara M Golden; Dean G Karahalios
Journal:  Spine J       Date:  2013-03-21       Impact factor: 4.166

Review 7.  Local anesthetic myotoxicity.

Authors:  Wolfgang Zink; Bernhard M Graf
Journal:  Reg Anesth Pain Med       Date:  2004 Jul-Aug       Impact factor: 6.288

8.  Desmoid Tumor Formation following Posterior Spinal Instrumentation Placement.

Authors:  Varun Puvanesarajah; Ioan A Lina; Jason A Liauw; Wesley Hsu; Peter C Burger; Timothy F Witham
Journal:  Evid Based Spine Care J       Date:  2013-10
  8 in total

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