Literature DB >> 34395781

Quantitative ChIP-seq by Adding Spike-in from Another Species.

Kongyan Niu1, Rui Liu2, Nan Liu1.   

Abstract

Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is a routine procedure in the lab; however, epigenome-wide quantitative comparison among independent ChIP-seq experiments remains a challenge. Here, we contribute an experimental protocol combined with a computational workflow allowing quantitative and comparative assessment of epigenome using animal tissues.
Copyright © The Authors; exclusive licensee Bio-protocol LLC.

Entities:  

Keywords:  Drosophila; Epigenome; H3K27me3; Quantitative ChIP-seq; Spike-in

Year:  2018        PMID： 34395781      PMCID： PMC8328608          DOI： 10.21769/BioProtoc.2981

Source DB:  PubMed          Journal:  Bio Protoc        ISSN： 2331-8325


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