Literature DB >> 34393671

Environmental Toxins Are a Major Cause of Bone Loss.

Joseph Pizzorno, Lara Pizzorno.   

Abstract

The environmental metals cadmium, lead, and mercury, and chemicals such as pesticides, phthalates, and bisphenols, disrupt bone metabolism in many ways. Body levels of these toxins directly correlate, in a dose-dependent manner, with risk of fracture and osteoporosis. This editorial provides a brief summary of key research showing mechanisms of damage, sources, and key strategies to decrease body load.
Copyright © 2021 InnoVision Professional Media Inc.

Entities:  

Year:  2021        PMID: 34393671      PMCID: PMC8352419     

Source DB:  PubMed          Journal:  Integr Med (Encinitas)        ISSN: 1546-993X


  32 in total

1.  Bone lead (Pb) content at the tibia is associated with thinner distal tibia cortices and lower volumetric bone density in postmenopausal women.

Authors:  Andy K O Wong; Karen A Beattie; Aakash Bhargava; Marco Cheung; Colin E Webber; David R Chettle; Alexandra Papaioannou; Jonathan D Adachi
Journal:  Bone       Date:  2015-05-15       Impact factor: 4.398

Review 2.  Evidence Supporting a Phased Immuno-physiological Approach to COVID-19 From Prevention Through Recovery.

Authors:  S F Yanuck; J Pizzorno; H Messier; K N Fitzgerald
Journal:  Integr Med (Encinitas)       Date:  2020

3.  Long-term cadmium exposure and the association with bone mineral density and fractures in a population-based study among women.

Authors:  Annette Engström; Karl Michaëlsson; Yasushi Suwazono; Alicja Wolk; Marie Vahter; Agneta Akesson
Journal:  J Bone Miner Res       Date:  2011-03       Impact factor: 6.741

4.  Increased level of organochlorine pesticides in chronic kidney disease patients of unknown etiology: role of GSTM1/GSTT1 polymorphism.

Authors:  Manushi Siddarth; Sudip K Datta; Md Mustafa; Rafat S Ahmed; Basu D Banerjee; Om P Kalra; Ashok K Tripathi
Journal:  Chemosphere       Date:  2013-11-09       Impact factor: 7.086

5.  Cadmium may be a risk factor for osteoporosis.

Authors:  L Järup; T Alfvén; B Persson; G Toss; C G Elinder
Journal:  Occup Environ Med       Date:  1998-07       Impact factor: 4.402

6.  Metabonomic analysis of the joint toxic action of long-term low-level exposure to a mixture of four organophosphate pesticides in rat plasma.

Authors:  Longfei Du; Sifan Li; Lei Qi; Yurong Hou; Yan Zeng; Wei Xu; Hong Wang; Xiujuan Zhao; Changhao Sun
Journal:  Mol Biosyst       Date:  2014-05

7.  Dietary intervention and DEHP reduction.

Authors:  Stephen P Risotto
Journal:  Environ Health Perspect       Date:  2011-09       Impact factor: 9.031

8.  Urinary BPA and Phthalate Metabolite Concentrations and Plasma Vitamin D Levels in Pregnant Women: A Repeated Measures Analysis.

Authors:  Lauren E Johns; Kelly K Ferguson; David E Cantonwine; Thomas F McElrath; Bhramar Mukherjee; John D Meeker
Journal:  Environ Health Perspect       Date:  2017-08-31       Impact factor: 9.031

9.  Urinary cadmium and osteoporosis in U.S. Women >or= 50 years of age: NHANES 1988-1994 and 1999-2004.

Authors:  Carolyn M Gallagher; John S Kovach; Jaymie R Meliker
Journal:  Environ Health Perspect       Date:  2008-06-13       Impact factor: 9.031

Review 10.  A Review on the Effects of Bisphenol A and Its Derivatives on Skeletal Health.

Authors:  Kok-Yong Chin; Kok-Lun Pang; Wun Fui Mark-Lee
Journal:  Int J Med Sci       Date:  2018-06-22       Impact factor: 3.738

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