AIM: We evaluated the delay in stroke reperfusion therapy between the pre-coronavirus disease 2019 (COVID-19) period and the with-COVID-19 period, and compared this delay between each phase of the with-COVID-19 period. METHODS: Patients with acute ischemic stroke (AIS) undergoing intravenous thrombolysis and/or mechanical thrombectomy were selected from our single-center prospective registry. The time to perform reperfusion therapy were compared between patients admitted from March 2019 to February 2020 (pre-COVID-19 group) and those from March 2020 to February 2021 (with-COVID-19 group). Patients in the with-COVID-19 group were further divided into three 4-month-long subgroups (first-phase: March to June 2020; second-phase: July to October 2020; third-phase: November 2020 to February 2021), and the time delay of reperfusion therapy were compared between these subgroups. RESULTS: Of 1,260 patients with AIS hospitalized in the study period, 265 patients were examined. Compared with the pre-COVID-19 group (133 patients; median age, 79 years), the with-COVID-19 group (132 patients; median age, 79 years) had a longer median door-to-imaging time (25 min vs. 27 min, P=0.04), and a longer door-to-groin puncture time (65 min vs. 72 min, P=0.02). In the three 4-month-long subgroups, the median door-to-needle time (49 min, 43 min, and 38 min, respectively; P=0.04) and door-to-groin puncture time (83 min, 70 min, and 61 min, P＜0.01, respectively) decreased significantly during the with-COVID-19 period. CONCLUSIONS: The delay in reperfusion therapy increased during the with-COVID-19 period compared with the pre-COVID-19 period. However, the door-to-needle time and door-to-groin puncture time decreased as time elapsed during the with-COVID-19 period. CLINICALTRIALS: gov Identifier: NCT02251665.
AIM: We evaluated the delay in stroke reperfusion therapy between the pre-coronavirus disease 2019 (COVID-19) period and the with-COVID-19 period, and compared this delay between each phase of the with-COVID-19 period. METHODS: Patients with acute ischemic stroke (AIS) undergoing intravenous thrombolysis and/or mechanical thrombectomy were selected from our single-center prospective registry. The time to perform reperfusion therapy were compared between patients admitted from March 2019 to February 2020 (pre-COVID-19 group) and those from March 2020 to February 2021 (with-COVID-19 group). Patients in the with-COVID-19 group were further divided into three 4-month-long subgroups (first-phase: March to June 2020; second-phase: July to October 2020; third-phase: November 2020 to February 2021), and the time delay of reperfusion therapy were compared between these subgroups. RESULTS: Of 1,260 patients with AIS hospitalized in the study period, 265 patients were examined. Compared with the pre-COVID-19 group (133 patients; median age, 79 years), the with-COVID-19 group (132 patients; median age, 79 years) had a longer median door-to-imaging time (25 min vs. 27 min, P=0.04), and a longer door-to-groin puncture time (65 min vs. 72 min, P=0.02). In the three 4-month-long subgroups, the median door-to-needle time (49 min, 43 min, and 38 min, respectively; P=0.04) and door-to-groin puncture time (83 min, 70 min, and 61 min, P＜0.01, respectively) decreased significantly during the with-COVID-19 period. CONCLUSIONS: The delay in reperfusion therapy increased during the with-COVID-19 period compared with the pre-COVID-19 period. However, the door-to-needle time and door-to-groin puncture time decreased as time elapsed during the with-COVID-19 period. CLINICALTRIALS: gov Identifier: NCT02251665.
Authors: Pratyaksh K Srivastava; Shuaiqi Zhang; Ying Xian; Hanzhang Xu; Christine Rutan; Heather M Alger; Jason Walchok; Joseph Williams; James A de Lemos; Marquita R Decker-Palmer; Brooke Alhanti; Mitchell S V Elkind; Steve R Messé; Eric E Smith; Lee H Schwamm; Gregg C Fonarow Journal: Stroke Date: 2021-03-17 Impact factor: 7.914
Authors: Kay-Cheong Teo; William C Y Leung; Yuen-Kwun Wong; Roxanna K C Liu; Anna H Y Chan; Olivia M Y Choi; Wing-Man Kwok; Kung-Ki Leung; Man-Yu Tse; Raymond T F Cheung; Anderson Chun-On Tsang; Kui Kai Lau Journal: Stroke Date: 2020-05-20 Impact factor: 7.914
Authors: Alexandra L Czap; James E Siegler; Alicia M Zha; Jacob Sebaugh; Ameer E Hassan; Julie G Shulman; Mohamad Abdalkader; Thanh N Nguyen; Italo Linfante; Amy Kathryn Starosciak; Santiago Ortega-Gutierrez; Mudassir Farooqui; Darko Quispe-Orozco; Nirav A Vora; Vivek Rai; Raul G Nogueira; Diogo C Haussen; Dinesh V Jillella; Ameena Rana; Siyuan Yu; Jesse M Thon; Osama O Zaidat; Priyank Khandelwal; Ivo Bach; Sunil A Sheth; Ashutosh P Jadhav; Shashvat M Desai; Tudor G Jovin; David S Liebeskind Journal: J Neurointerv Surg Date: 2021-02-08 Impact factor: 5.836
Authors: Paul J Nederkoorn; Stefan T Engelter; Henrik Gensicke; Valerian L Altersberger; Lotte J Stolze; Mirjam R Heldner; Hilde Henon; Nicolas Martinez-Majander; Christian Hametner; Annika Nordanstig; Andrea Zini; Stefania Nannoni; Bruno Gonçalves; Christian H Nolte; Philipp Baumgartner; Andreas Kastrup; Panagiotis Papanagiotou; Georg Kägi; Ronen R Leker; Marialuisa Zedde; Alessandro Padovani; Alessandro Pezzini; Visnja Padjen; Carlo W Cereda; Georges Ntaios; Leo H Bonati; Leon A Rinkel; Urs Fischer; Jan F Scheitz; Susanne Wegener; Guillaume Turc; Patrik Michel; Mauro Gentile; Alexandros Rentzos; Peter A Ringleb; Sami Curtze; Charlotte Cordonnier; Marcel Arnold Journal: Stroke Date: 2021-04-01 Impact factor: 7.914
Authors: Raul G Nogueira; Mohamad Abdalkader; Muhammed M Qureshi; Michael R Frankel; Ossama Yassin Mansour; Hiroshi Yamagami; Zhongming Qiu; Mehdi Farhoudi; James E Siegler; Shadi Yaghi; Eytan Raz; Nobuyuki Sakai; Nobuyuki Ohara; Michel Piotin; Laura Mechtouff; Omer Eker; Vanessa Chalumeau; Timothy J Kleinig; Raoul Pop; Jianmin Liu; Hugh S Winters; Xianjin Shang; Alejandro Rodriguez Vasquez; Jordi Blasco; Juan F Arenillas; Mario Martinez-Galdamez; Alex Brehm; Marios-Nikos Psychogios; Pedro Lylyk; Diogo C Haussen; Alhamza R Al-Bayati; Mahmoud H Mohammaden; Luísa Fonseca; M Luís Silva; Francisco Montalverne; Leonardo Renieri; Salvatore Mangiafico; Urs Fischer; Jan Gralla; Donald Frei; Chandril Chugh; Brijesh P Mehta; Simon Nagel; Markus Mohlenbruch; Santiago Ortega-Gutierrez; Mudassir Farooqui; Ameer E Hassan; Allan Taylor; Bertrand Lapergue; Arturo Consoli; Bruce Cv Campbell; Malveeka Sharma; Melanie Walker; Noel Van Horn; Jens Fiehler; Huy Thang Nguyen; Quoc T Nguyen; Daisuke Watanabe; Hao Zhang; Huynh V Le; Viet Q Nguyen; Ruchir Shah; Thomas Devlin; Priyank Khandelwal; Italo Linfante; Wazim Izzath; Pablo M Lavados; Veronica V Olavarría; Gisele Sampaio Silva; Anna Verena de Carvalho Sousa; Jawad Kirmani; Martin Bendszus; Tatsuo Amano; Ryoo Yamamoto; Ryosuke Doijiri; Naoki Tokuda; Takehiro Yamada; Tadashi Terasaki; Yukako Yazawa; Jane G Morris; Emma Griffin; John Thornton; Pascale Lavoie; Charles Matouk; Michael D Hill; Andrew M Demchuk; Monika Killer-Oberpfalzer; Fadi Nahab; Dorothea Altschul; Anna Ramos-Pachón; Natalia Pérez de la Ossa; Raghid Kikano; William Boisseau; Gregory Walker; Steve M Cordina; Ajit Puri; Anna Luisa Kuhn; Dheeraj Gandhi; Pankajavalli Ramakrishnan; Roberta Novakovic-White; Alex Chebl; Odysseas Kargiotis; Alexandra Czap; Alicia Zha; Hesham E Masoud; Carlos Lopez; David Ozretic; Fawaz Al-Mufti; Wenjie Zie; Zhenhui Duan; Zhengzhou Yuan; Wenguo Huang; Yonggang Hao; Jun Luo; Vladimir Kalousek; Romain Bourcier; Romain Guile; Steven Hetts; Hosam M Al-Jehani; Adel AlHazzani; Elyar Sadeghi-Hokmabadi; Mohamed Teleb; Jeremy Payne; Jin Soo Lee; Ji Man Hong; Sung-Il Sohn; Yang-Ha Hwang; Dong Hoon Shin; Hong Gee Roh; Randy Edgell; Rakesh Khatri; Ainsley Smith; Amer Malik; David Liebeskind; Nabeel Herial; Pascal Jabbour; Pedro Magalhaes; Atilla Ozcan Ozdemir; Ozlem Aykac; Takeshi Uwatoko; Tomohisa Dembo; Hisao Shimizu; Yuri Sugiura; Fumio Miyashita; Hiroki Fukuda; Kosuke Miyake; Junsuke Shimbo; Yusuke Sugimura; Andre Beer-Furlan; Krishna Joshi; Luciana Catanese; Daniel Giansante Abud; Octavio Giansante Neto; Masoud Mehrpour; Amal Al Hashmi; Mahar Saqqur; Abdulrahman Mostafa; Johanna T Fifi; Syed Hussain; Seby John; Rishi Gupta; Rotem Sivan-Hoffmann; Anna Reznik; Achmad Fidaus Sani; Serdar Geyik; Eşref Akıl; Anchalee Churojana; Abdoreza Ghoreishi; Mohammad Saadatnia; Ehsan Sharifipour; Alice Ma; Ken Faulder; Teddy Wu; Lester Leung; Adel Malek; Barbara Voetsch; Ajay Wakhloo; Rodrigo Rivera; Danny Moises Barrientos Iman; Aleksandra Pikula; Vasileios-Arsenios Lioutas; Gotz Thomalla; Lee Birnbaum; Paolo Machi; Gianmarco Bernava; Mollie McDermott; Dawn Kleindorfer; Ken Wong; Mary S Patterson; Jose Antonio Fiorot; Vikram Huded; William Mack; Matthew Tenser; Clifford Eskey; Sumeet Multani; Michael Kelly; Vallabh Janardhan; Oriana Cornett; Varsha Singh; Yuichi Murayama; Maxim Mokin; Pengfei Yang; Xiaoxi Zhang; Congguo Yin; Hongxing Han; Ya Peng; Wenhuo Chen; Roberto Crosa; Michel Eli Frudit; Jeyaraj D Pandian; Anirudh Kulkarni; Yoshiki Yagita; Yohei Takenobu; Yuji Matsumaru; Satoshi Yamada; Ryuhei Kono; Takuya Kanamaru; Hidekazu Yamazaki; Manabu Sakaguchi; Kenichi Todo; Nobuaki Yamamoto; Kazutaka Sonoda; Tomoko Yoshida; Hiroyuki Hashimoto; Ichiro Nakahara; Elena Cora; David Volders; Celina Ducroux; Ashkan Shoamanesh; Johanna Ospel; Artem Kaliaev; Saima Ahmed; Umair Rashid; Leticia C Rebello; Vitor Mendes Pereira; Robert Fahed; Michael Chen; Sunil A Sheth; Lina Palaiodimou; Georgios Tsivgoulis; Ronil Chandra; Feliks Koyfman; Thomas Leung; Houman Khosravani; Sushrut Dharmadhikari; Giovanni Frisullo; Paolo Calabresi; Alexander Tsiskaridze; Nino Lobjanidze; Mikayel Grigoryan; Anna Czlonkowska; Diana Aguiar de Sousa; Jelle Demeestere; Conrad Liang; Navdeep Sangha; Helmi L Lutsep; Óscar Ayo-Martín; Antonio Cruz-Culebras; Anh D Tran; Chang Y Young; Charlotte Cordonnier; Francois Caparros; Maria Alonso De Lecinana; Blanca Fuentes; Dileep Yavagal; Tudor Jovin; Laurent Spelle; Jacques Moret; Pooja Khatri; Osama Zaidat; Jean Raymond; Sheila Martins; Thanh Nguyen Journal: Int J Stroke Date: 2021-03-29 Impact factor: 5.266
Authors: James E Siegler; Alicia M Zha; Alexandra L Czap; Santiago Ortega-Gutierrez; Mudassir Farooqui; David S Liebeskind; Shashvat M Desai; Ameer E Hassan; Amy K Starosciak; Italo Linfante; Vivek Rai; Jesse M Thon; Ryna Then; Mark E Heslin; Lauren Thau; Priyank Khandelwal; Mahmoud H Mohammaden; Diogo C Haussen; Raul G Nogueira; Dinesh V Jillella; Fadi Nahab; Artem Kaliaev; Thanh N Nguyen; Osama Zaidat; Tudor G Jovin; Ashutosh P Jhadav Journal: Stroke Date: 2020-11-30 Impact factor: 7.914