Akbaribazm Mohsen1, Khazaei Fatemeh1, Naseri Leila1, Pazhouhi Mona2, Zamanian Mohammad3, Khazaei Mozafar2. 1. Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah 6714869914, Iran. 2. Fertility and infertility research center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah 6714869914, Iran. 3. Seed and Plant Improvement Institute, Agricultural Research, Education, Extension Organization, Karaj 3135933151, Iran.
Abstract
OBJECTIVE: To review beneficial effects of red clover (Trifolium pratense L.) on biological processes. METHODS: A systematic review was carried out according tothe PRISMA checklist. Using MeSH keywords, 385 articles were extracted from national and international databases (PubMed, Science Direct, SID, and Google Scholar search engine) without time limit. After removing duplicates, 80 articles were reviewed. RESULTS: Our findings revealed that the compositions of red clover promote anti-oxidant and anti-cancer effects. Furthermore, they exude beneficial effects on cardiovascular functionand improvesymptoms of menopause. Also, these compounds can regulate blood glucose and lipid markers. The effects of the herb on have also been investigated on various tissues including endometrium, breast, skin and reproductive system. CONCLUSION: In recent studies, the anti-cancer effects of clover (Trifolium) extract co-administrated with standard drugs have been reportedin different cancers.
OBJECTIVE: To review beneficial effects of red clover (Trifolium pratense L.) on biological processes. METHODS: A systematic review was carried out according tothe PRISMA checklist. Using MeSH keywords, 385 articles were extracted from national and international databases (PubMed, Science Direct, SID, and Google Scholar search engine) without time limit. After removing duplicates, 80 articles were reviewed. RESULTS: Our findings revealed that the compositions of red clover promote anti-oxidant and anti-cancer effects. Furthermore, they exude beneficial effects on cardiovascular functionand improvesymptoms of menopause. Also, these compounds can regulate blood glucose and lipid markers. The effects of the herb on have also been investigated on various tissues including endometrium, breast, skin and reproductive system. CONCLUSION: In recent studies, the anti-cancer effects of clover (Trifolium) extract co-administrated with standard drugs have been reportedin different cancers.