| Literature DB >> 34392132 |
Giulia Maria Sancesario1, Giulia Di Lazzaro2, Piergiorgio Grillo3, Benedetta Biticchi1, Emilia Giannella1, Mohammad Alwardat4, Massimo Pieri5, Sergio Bernardini5, Nicola Biagio Mercuri6, Antonio Pisani7, Tommaso Schirinzi8.
Abstract
We measured α-Klotho in CSF and serum of PD patients at early stage of the disease, finding two distinct pools, the first increased, the second reduced. CSF α-Klotho was inversely associated with CSF α-synuclein levels. Our preliminary results suggest α-Klotho as potential biomarker or therapeutic target in PD.Entities:
Keywords: Biomarkers; Blood; CSF; Parkinson's disease; α-Klotho
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Year: 2021 PMID： 34392132 DOI： 10.1016/j.parkreldis.2021.08.004
Source DB: PubMed Journal: Parkinsonism Relat Disord ISSN： 1353-8020 Impact factor: 4.891