Concepción Núñez López1, Juan Manuel González de Abreu1, Verónica Pérez-Blanco2, Rosa de Miguel Buckley3, María Pilar Romero Gómez4, Marta Díaz-Menéndez5. 1. Occupational Health Department, La Paz University Hospital, Madrid, Spain. 2. Preventive Medicine Department, La Paz University Hospital, Madrid, Spain. 3. Infectious Disease Unit, Internal Medicine Department, La Paz University Hospital, Madrid, Spain. 4. Microbiology Department, La Paz University Hospital, Madrid, Spain. 5. Infectious Disease Unit, Internal Medicine Department, La Paz University Hospital, Madrid, Spain. Electronic address: marta.diaz@salud.madrid.org.
Abstract
INTRODUCTION: Frontline health care workers (HCW) have higher risk than the general population to become infected by SARS.CoV.2, so they were a priority group for Covid-19 vaccine administration. We compared the incidence and prevalence of HCW infected pre-and post-vaccination with the BNT162b2 mRNA COVID-19 vaccine. MATERIAL AND METHODS: Prospective observational study carried out between 01/12/20 and 07/03/21 in La Paz University Hospital, Madrid (Spain). SARS.CoV.2 positive cases in HCW after vaccination were collected and compared to those hospitalized COVID-19 patients at the same hospital. RESULTS: Two weeks after finishing the first round of vaccinations daily new cases of HCW infections (symptomatic and asymptomatic) decreased substantially and cumulative cases of infected HCW and hospitalized COVID-19 patients started to diverge. No new positive cases of HCW infection were registered seven days after the second dose of BNT162b2 mRNA COVID-19 vaccine. CONCLUSIONS: BNT162b2 mRNA COVID-19 vaccine is highly effective in Spanish HCW.
INTRODUCTION: Frontline health care workers (HCW) have higher risk than the general population to become infected by SARS.CoV.2, so they were a priority group for Covid-19 vaccine administration. We compared the incidence and prevalence of HCW infected pre-and post-vaccination with the BNT162b2 mRNA COVID-19 vaccine. MATERIAL AND METHODS: Prospective observational study carried out between 01/12/20 and 07/03/21 in La Paz University Hospital, Madrid (Spain). SARS.CoV.2 positive cases in HCW after vaccination were collected and compared to those hospitalized COVID-19 patients at the same hospital. RESULTS: Two weeks after finishing the first round of vaccinations daily new cases of HCW infections (symptomatic and asymptomatic) decreased substantially and cumulative cases of infected HCW and hospitalized COVID-19 patients started to diverge. No new positive cases of HCW infection were registered seven days after the second dose of BNT162b2 mRNA COVID-19 vaccine. CONCLUSIONS: BNT162b2 mRNA COVID-19 vaccine is highly effective in Spanish HCW.
Authors: Mireia Utzet; Fernando G Benavides; Rocío Villar; Andrea Burón; Maria Sala; Luis-Eugenio López; Pau Gomar; Xavier Castells; Pilar Diaz; José María Ramada; Consol Serra Journal: Int J Environ Res Public Health Date: 2022-03-18 Impact factor: 3.390