Literature DB >> 3438743

Methylcyclopentadienyl manganese tricarbonyl (MMT) in petrol: the toxicological issues.

P J Abbott1.   

Abstract

Methylcyclopentadienyl manganese tricarbonyl (MMT), when used as an octane improver in petrol, leads to increased airborne levels of manganese in the form of Mn3O4. The potential health effects of increased airborne manganese are considered in this paper. Manganese, unlike lead which it can replace in petrol, is a normal and essential component of the human diet and the intake from airborne manganese is slight by comparison to the normal dietary intake. The major toxicological effects of manganese, observed after long occupational exposure, are on the lung (manganese pneumonia) and the central nervous system (manganism). The small increase in airborne manganese from the use of MMT in petrol is 3-4 orders of magnitude lower than the level required to produce toxic symptoms of manganese exposure, even in areas of high traffic density, and no health risk from the use of MMT is likely.

Entities:  

Mesh:

Substances:

Year:  1987        PMID: 3438743     DOI: 10.1016/0048-9697(87)90215-4

Source DB:  PubMed          Journal:  Sci Total Environ        ISSN: 0048-9697            Impact factor:   7.963


  4 in total

1.  Rat brain endothelial cells are a target of manganese toxicity.

Authors:  Ana Paula Marreilha dos Santos; Dejan Milatovic; Catherine Au; Zhaobao Yin; Maria Camila C Batoreu; Michael Aschner
Journal:  Brain Res       Date:  2010-02-17       Impact factor: 3.252

2.  Environmental and occupational exposure to manganese: a multimedia assessment.

Authors:  S Loranger; J Zayed
Journal:  Int Arch Occup Environ Health       Date:  1995       Impact factor: 3.015

3.  Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans.

Authors:  Alexandre Benedetto; Catherine Au; Daiana Silva Avila; Dejan Milatovic; Michael Aschner
Journal:  PLoS Genet       Date:  2010-08-26       Impact factor: 5.917

Review 4.  Manganese (Mn) and iron (Fe): interdependency of transport and regulation.

Authors:  Vanessa A Fitsanakis; Na Zhang; Stephanie Garcia; Michael Aschner
Journal:  Neurotox Res       Date:  2009-11-18       Impact factor: 3.911

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.