Literature DB >> 34380949

Total Artificial Heart Computational Fluid Dynamics: Modeling of Stator Bore Design Effects on Journal-Bearing Performance.

Maryam Khelghatibana1, Mark S Goodin2, Michael Yaksh3, David J Horvath4, Barry D Kuban5, Kiyotaka Fukamachi5,6, Jamshid H Karimov5,6.   

Abstract

Cleveland Clinic's continuous-flow total artificial heart (CFTAH) is a double-ended centrifugal blood pump that has a single rotating assembly with an embedded magnet, which is axially and radially suspended by a balance of magnetic and hydrodynamic forces. The key to the radial suspension is a radial offset between the stator bearing bore and the magnet's steel laminations. This offset applies a radial magnetic force, which is balanced by a hydrodynamic force as the rotating assembly moves to a "force-balanced" radial position. The journal-bearing blood passage is a narrow flow path between the left and right impellers. The intent of this study was to determine the impact of the stator-bearing bore radius on the journal-bearing hydraulic performance while satisfying the geometric design constraints imposed by the pump and motor configuration. Electromagnetic forces on the journal bearing were calculated using the ANSYS EMAG program, Version 18 (ANSYS, Canonsburg, PA). ANSYS CFX Version 19.2 was then used to model the journal-bearing flow paths of the most recent design of the CFTAH. A transient, moving mesh approach was used to locate the steady state, force-balanced position of the rotating assembly. The blood was modeled as a non-Newtonian fluid. The computational fluid dynamics simulations showed that by increasing stator bore radius, rotor power, stator wall average shear stress, and blood residence time in journal-bearing decrease, while blood net flow rate through the bearing increases. The results were used to select a new bearing design that provides an improved performance compared with the baseline design. The performance of the new CFTAH-bearing design will be confirmed through upcoming in vitro and in vivo testing.
Copyright © ASAIO 2021.

Entities:  

Mesh:

Year:  2022        PMID: 34380949      PMCID: PMC8828802          DOI: 10.1097/MAT.0000000000001556

Source DB:  PubMed          Journal:  ASAIO J        ISSN: 1058-2916            Impact factor:   3.826


  17 in total

1.  Concept for a new hydrodynamic blood bearing for miniature blood pumps.

Authors:  Thomas Kink; Helmut Reul
Journal:  Artif Organs       Date:  2004-10       Impact factor: 3.094

2.  Effects of the non-Newtonian viscosity of blood on flows in a diseased arterial vessel. Part 1: Steady flows.

Authors:  Y I Cho; K R Kensey
Journal:  Biorheology       Date:  1991       Impact factor: 1.875

3.  A novel design of spiral groove bearing in a hydrodynamically levitated centrifugal rotary blood pump.

Authors:  Qing Han; Jun Zou; Xiaodong Ruan; Xin Fu; Huayong Yang
Journal:  Artif Organs       Date:  2012-07-02       Impact factor: 3.094

4.  First report of 90-day support of 2 calves with a continuous-flow total artificial heart.

Authors:  Jamshid H Karimov; Nader Moazami; Mariko Kobayashi; Shiva Sale; Kimberly Such; Nicole Byram; Gengo Sunagawa; David Horvath; Shengqiang Gao; Barry Kuban; Leonard A R Golding; Kiyotaka Fukamachi
Journal:  J Thorac Cardiovasc Surg       Date:  2015-06-18       Impact factor: 5.209

5.  Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association.

Authors:  Emelia J Benjamin; Paul Muntner; Alvaro Alonso; Marcio S Bittencourt; Clifton W Callaway; April P Carson; Alanna M Chamberlain; Alexander R Chang; Susan Cheng; Sandeep R Das; Francesca N Delling; Luc Djousse; Mitchell S V Elkind; Jane F Ferguson; Myriam Fornage; Lori Chaffin Jordan; Sadiya S Khan; Brett M Kissela; Kristen L Knutson; Tak W Kwan; Daniel T Lackland; Tené T Lewis; Judith H Lichtman; Chris T Longenecker; Matthew Shane Loop; Pamela L Lutsey; Seth S Martin; Kunihiro Matsushita; Andrew E Moran; Michael E Mussolino; Martin O'Flaherty; Ambarish Pandey; Amanda M Perak; Wayne D Rosamond; Gregory A Roth; Uchechukwu K A Sampson; Gary M Satou; Emily B Schroeder; Svati H Shah; Nicole L Spartano; Andrew Stokes; David L Tirschwell; Connie W Tsao; Mintu P Turakhia; Lisa B VanWagner; John T Wilkins; Sally S Wong; Salim S Virani
Journal:  Circulation       Date:  2019-03-05       Impact factor: 29.690

6.  Red blood cell damage by shear stress.

Authors:  L B Leverett; J D Hellums; C P Alfrey; E C Lynch
Journal:  Biophys J       Date:  1972-03       Impact factor: 4.033

Review 7.  Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association.

Authors:  Emelia J Benjamin; Salim S Virani; Clifton W Callaway; Alanna M Chamberlain; Alexander R Chang; Susan Cheng; Stephanie E Chiuve; Mary Cushman; Francesca N Delling; Rajat Deo; Sarah D de Ferranti; Jane F Ferguson; Myriam Fornage; Cathleen Gillespie; Carmen R Isasi; Monik C Jiménez; Lori Chaffin Jordan; Suzanne E Judd; Daniel Lackland; Judith H Lichtman; Lynda Lisabeth; Simin Liu; Chris T Longenecker; Pamela L Lutsey; Jason S Mackey; David B Matchar; Kunihiro Matsushita; Michael E Mussolino; Khurram Nasir; Martin O'Flaherty; Latha P Palaniappan; Ambarish Pandey; Dilip K Pandey; Mathew J Reeves; Matthew D Ritchey; Carlos J Rodriguez; Gregory A Roth; Wayne D Rosamond; Uchechukwu K A Sampson; Gary M Satou; Svati H Shah; Nicole L Spartano; David L Tirschwell; Connie W Tsao; Jenifer H Voeks; Joshua Z Willey; John T Wilkins; Jason Hy Wu; Heather M Alger; Sally S Wong; Paul Muntner
Journal:  Circulation       Date:  2018-01-31       Impact factor: 29.690

8.  Morbidity and mortality in heart transplant candidates supported with mechanical circulatory support: is reappraisal of the current United network for organ sharing thoracic organ allocation policy justified?

Authors:  Omar Wever-Pinzon; Stavros G Drakos; Abdallah G Kfoury; Jose N Nativi; Edward M Gilbert; Melanie Everitt; Rami Alharethi; Kim Brunisholz; Feras M Bader; Dean Y Li; Craig H Selzman; Josef Stehlik
Journal:  Circulation       Date:  2012-12-27       Impact factor: 29.690

9.  An innovative, sensorless, pulsatile, continuous-flow total artificial heart: device design and initial in vitro study.

Authors:  Kiyotaka Fukamachi; David J Horvath; Alex L Massiello; Hideyuki Fumoto; Tetsuya Horai; Santosh Rao; Leonard A R Golding
Journal:  J Heart Lung Transplant       Date:  2009-09-26       Impact factor: 10.247

10.  The Impact of Pulsatile Flow on Suspension Force for Hydrodynamically Levitated Blood Pump.

Authors:  Yang Fu; Yimin Hu; Feng Huang; Maoying Zhou
Journal:  J Healthc Eng       Date:  2019-06-03       Impact factor: 2.682

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.