Michael Wandling1, Joseph Cuschieri2, Rosemary Kozar3, Lindsay O'Meara3, Amanda Celii4, William Starr4, Clay Cothren Burlew5, S Rob Todd6, Alejandro de Leon6, Robert C McIntyre7, Shane Urban7, Walt L Biffl8, Dunya Bayat8, Julie Dunn9, Kimberly Peck10, Alexandra S Rooney10, Lucy Z Kornblith11, Rachael A Callcut11, Daniel I Lollar12, Eric Ambroz12, Stefan W Leichtle13, Michel B Aboutanos13, Thomas Schroeppel14, Elizabeth A Hennessy14, Rachel Russo15, Michelle McNutt16. 1. McGovern Medical School at UT Health, 6410 Fannin St, Houston, TX 77030, USA. 2. University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA. 3. University of Maryland School of Medicine, 655 W Baltimore St S, Baltimore, MD 21201, USA. 4. Oklahoma University Health Science Center, 865 Research Pkwy, Oklahoma, OK 73104, USA. 5. Denver Health Medical Center, 777 Bannock St, Denver, CO 80204, USA. 6. Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA. 7. University of Colorado, 13001 E 17(th) Pl, Aurora, CO 80045, USA. 8. Scripps Memorial Hospital La Jolla, 9888 Genesee Ave, San Diego, CA 92037, USA. 9. UC Health Medical Center of the Rockies, 2500 Rocky Mountain Ave, Loveland, CO 80538, USA. 10. Scripps Mercy Hospital San Diego, 4077 Fifth Ave, San Diego, CA 92103, USA. 11. University of California San Francisco, 505 Parnassus Ave, San Francisco, CA 94143, USA. 12. Virginia Tech Carilion School of Medicine, 2 Riverside Circle, Roanoke, VA 24016, USA. 13. Virginia Commonwealth University Medical Center, 1204 E Marshal St #4-100, Richmond, VA 23298, USA. 14. UCHealth Memorial Hospital Central, 1400 E Boulder St, Colorado Springs, CO 80909, USA. 15. University of Michigan, 1301 Catherine St, Ann Arbor, MI 48109, USA. 16. McGovern Medical School at UT Health, 6410 Fannin St, Houston, TX 77030, USA. Electronic address: Michelle.K.McNutt@uth.tmc.edu.
Abstract
INTRODUCTION: The Bowel Injury Prediction Score (BIPS) is a tool for identifying patients at risk for blunt bowel and mesenteric injury (BBMI) requiring surgery. BIPS is calculated by assigning one point for each of the following: (1) WBC ≥ 17,000, (2) abdominal tenderness, and (3) injury grade ≥ 4 (mesenteric contusion or hematoma with bowel wall thickening or adjacent interloop fluid collection) on CT scan. A total score ≥ 2 is associated with BBMI requiring surgery. We aimed to validate the BIPS as a predictor for patients with BBMIs requiring operative intervention in a multi-center prospective study. MATERIALS AND METHODS: Patients were prospectively enrolled at 15 U.S. trauma centers following blunt trauma with suspicion of BBMI on CT scan between July 1, 2018 and July 31, 2019. The BIPS was calculated for each patient enrolled in the study. RESULTS: Of 313 patients, 38% had BBMI requiring operative intervention. Patients were significantly more likely to require surgery in the presence of abdominal tenderness (OR, 3.6; 95% CI, 1.6-8.0) and CT grade ≥ 4 (OR, 11.7; 95% CI, 5.7-23.7). Patients with a BIPS ≥ 2 were more than ten times more likely to require laparotomy than those with a BIPS < 2 (OR, 10.1; 95% CI, 5.0-20.4). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a BIPS ≥ 2 for BBMI requiring surgery was 72% (CI 0.6-0.8), 78% (CI 0.7-0.8), 67% (CI 0.6-0.8), and 82% (CI 0.8-0.9), respectively. The AUROC curve for BIPS ≥ 2 was 0.75. The sensitivity, specificity, PPV, and NPV of a BIPS ≥ 2 for BBMI requiring surgery in patients with severe alteration in mental status (GCS 3-8) was 70% (CI 0.5-0.9), 92% (CI 0.8-1.0), 82% (CI 0.6-1.0), and 86% (CI 0.7-1.0), respectively. CONCLUSION: This prospective multi-center trial validates BIPS as a predictor of BBMI requiring surgery. Calculation of BIPS during the initial evaluation of trauma patients is a useful adjunct to help general surgeons taking trauma call determine operative versus non-operative management of patients with BBMI including those with severe alteration in mental status.
INTRODUCTION: The Bowel Injury Prediction Score (BIPS) is a tool for identifying patients at risk for blunt bowel and mesenteric injury (BBMI) requiring surgery. BIPS is calculated by assigning one point for each of the following: (1) WBC ≥ 17,000, (2) abdominal tenderness, and (3) injury grade ≥ 4 (mesenteric contusion or hematoma with bowel wall thickening or adjacent interloop fluid collection) on CT scan. A total score ≥ 2 is associated with BBMI requiring surgery. We aimed to validate the BIPS as a predictor for patients with BBMIs requiring operative intervention in a multi-center prospective study. MATERIALS AND METHODS: Patients were prospectively enrolled at 15 U.S. trauma centers following blunt trauma with suspicion of BBMI on CT scan between July 1, 2018 and July 31, 2019. The BIPS was calculated for each patient enrolled in the study. RESULTS: Of 313 patients, 38% had BBMI requiring operative intervention. Patients were significantly more likely to require surgery in the presence of abdominal tenderness (OR, 3.6; 95% CI, 1.6-8.0) and CT grade ≥ 4 (OR, 11.7; 95% CI, 5.7-23.7). Patients with a BIPS ≥ 2 were more than ten times more likely to require laparotomy than those with a BIPS < 2 (OR, 10.1; 95% CI, 5.0-20.4). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a BIPS ≥ 2 for BBMI requiring surgery was 72% (CI 0.6-0.8), 78% (CI 0.7-0.8), 67% (CI 0.6-0.8), and 82% (CI 0.8-0.9), respectively. The AUROC curve for BIPS ≥ 2 was 0.75. The sensitivity, specificity, PPV, and NPV of a BIPS ≥ 2 for BBMI requiring surgery in patients with severe alteration in mental status (GCS 3-8) was 70% (CI 0.5-0.9), 92% (CI 0.8-1.0), 82% (CI 0.6-1.0), and 86% (CI 0.7-1.0), respectively. CONCLUSION: This prospective multi-center trial validates BIPS as a predictor of BBMI requiring surgery. Calculation of BIPS during the initial evaluation of trauma patients is a useful adjunct to help general surgeons taking trauma call determine operative versus non-operative management of patients with BBMI including those with severe alteration in mental status.
Authors: Luke Smyth; Cino Bendinelli; Nicholas Lee; Matthew G Reeds; Eu Jhin Loh; Francesco Amico; Zsolt J Balogh; Salomone Di Saverio; Dieter Weber; Richard Peter Ten Broek; Fikri M Abu-Zidan; Giampiero Campanelli; Solomon Gurmu Beka; Massimo Chiarugi; Vishal G Shelat; Edward Tan; Ernest Moore; Luigi Bonavina; Rifat Latifi; Andreas Hecker; Jim Khan; Raul Coimbra; Giovanni D Tebala; Kjetil Søreide; Imtiaz Wani; Kenji Inaba; Andrew W Kirkpatrick; Kaoru Koike; Gabriele Sganga; Walter L Biffl; Osvaldo Chiara; Thomas M Scalea; Gustavo P Fraga; Andrew B Peitzman; Fausto Catena Journal: World J Emerg Surg Date: 2022-03-04 Impact factor: 5.469