| Literature DB >> 3437898 |
L Dailey1, S B Roberts, N Heintz.
Abstract
Specific DNA-binding and in vitro transcription activities of H4TF-1 and H4TF-2 are inactivated by chelating agents. Binding activity is restored by addition of Zn2+, and H4TF-2 is also reactivated by Fe2+. In contrast, preformed factor-DNA complexes are resistant to chelators. Therefore, metal ions are a required component of the H4TF-1 and H4TF-2 DNA-binding domains.Entities:
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Year: 1987 PMID: 3437898 PMCID: PMC368148 DOI: 10.1128/mcb.7.12.4582-4584.1987
Source DB: PubMed Journal: Mol Cell Biol ISSN: 0270-7306 Impact factor: 4.272