Literature DB >> 343784

Demonstration of chymosin (EC 3.4.23.4) in the stomach of newborn pig.

B Foltmann, P Lønblad, N H Axelsen.   

Abstract

The stomach of newborn pig contains a proteinase that is immunologically closely related to calf chymosin (rennin) (EC 3.4.23.4.). None of the pepsins from the stomach of adult pig is present in the newborn pig. Pig chymosin has optimal general proteolytic activity around pH 3.5. The ratio of milk-clotting activity to general proteolytic activity is about 30--70 times higher than that of pyloric and fundic pepsins.

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Year:  1978        PMID: 343784      PMCID: PMC1184183          DOI: 10.1042/bj1690425

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  7 in total

1.  STUDIES ON RENNIN. IX. ON THE LIMITED PROTEOLYSIS OF A-RENNIN AND THE PROTEOLYTIC ACTIVITY OF CHROMATOGRAPHICALLY PURIFIED FRACTIONS OF RENNIN.

Authors:  B FOLTMANN
Journal:  C R Trav Lab Carlsberg       Date:  1964

Review 2.  Pepsinogens, pepsins, and pepsin inhibitors.

Authors:  I M Samloff
Journal:  Gastroenterology       Date:  1971-04       Impact factor: 22.682

3.  Rennin and the gastric secretion of normal infants.

Authors:  F H Malpress
Journal:  Nature       Date:  1967-08-19       Impact factor: 49.962

4.  Comparison of the development of proteolytic activity in the abomasum of the preruminant calf with that in the stomach of the young rabbit and guinea-pig.

Authors:  M J Henschel
Journal:  Br J Nutr       Date:  1973-09       Impact factor: 3.718

5.  Immunochemical, chromatographic, and milk-clotting activity measurements for quantification of milk-clotting enzymes in bovine rennets.

Authors:  G A Rothe; N H Axelsen; P Johnk; B Foltmann
Journal:  J Dairy Res       Date:  1976-02       Impact factor: 1.904

6.  Immunochemical study and cellular localization of human pepsinogens during ontogenesis and in gastric cancers.

Authors:  H Hirsch-Marie; F Loisillier; J P Touboul; P Burtin
Journal:  Lab Invest       Date:  1976-06       Impact factor: 5.662

7.  Rennin and pepsin in stomachs of rats (Rattus norvegicus).

Authors:  C Kotts; R Jenness
Journal:  J Dairy Sci       Date:  1976-08       Impact factor: 4.034

  7 in total

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