Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Double-blind evaluation of clonazepam on periodic leg movements in sleep.

Literature DB >> 3437302

Double-blind evaluation of clonazepam on periodic leg movements in sleep.

Abstract

Treatment with clonazepam was studied in a group of 20 patients suffering from periodic movements in sleep, in a double-blind parallel group design. Eleven complained of excessive daytime sleepiness, and nine complained of insomnia. Ten patients received clonazepam, and 10 received placebo, over a period of 1 month. Clonazepam (0.5-2 mg per night) proved to be an effective treatment of periodic movements in sleep. Polysomnographic recordings demonstrated a significant decrease in the number of leg movements and a significant improvement in sleep parameters in the clonazepam group as compared with placebo. Subjective responses to treatment corroborated the sleep laboratory findings.

Entities: Chemical Disease Species

Mesh：

Substances：
Clonazepam

Year: 1987 PMID： 3437302 PMCID： PMC1032613 DOI： 10.1136/jnnp.50.12.1679

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

10 in total

1. Nocturnal myoclonus.

Authors: C P SYMONDS
Journal: J Neurol Neurosurg Psychiatry Date: 1953-08 Impact factor: 10.154

2. Sleep-related periodic myoclonus in patients complaining of insomnia.

Authors: C Guilleminault; D Raynal; E D Weitzman; W C Dement
Journal: Trans Am Neurol Assoc Date: 1975

3. Periodic leg movements in sleep: effect of clonazepam treatment.

Authors: N Ohanna; R Peled; A H Rubin; J Zomer; P Lavie
Journal: Neurology Date: 1985-03 Impact factor: 9.910

4. [Apropos of some nocturnal myoclonic manifestations. (Symonds' nocturnal myoclonus)].

Authors: E Lugaresi; G Coccagna; D Gambi; G B Ceroni; M Poppi
Journal: Rev Neurol (Paris) Date: 1966-09 Impact factor: 2.607

5. Effect of baclofen on sleep-related periodic leg movements.

Authors: C Guilleminault; W Flagg
Journal: Ann Neurol Date: 1984-03 Impact factor: 10.422

6. Descriptive epidemiology of Creutzfeldt-Jakob disease in Chile.

Authors: S Galvez; C Masters; C Gajdusek
Journal: Arch Neurol Date: 1980-01

7. Periodic movements in sleep (nocturnal myoclonus): relation to sleep disorders.

Authors: R M Coleman; C P Pollak; E D Weitzman
Journal: Ann Neurol Date: 1980-10 Impact factor: 10.422

8. Periodic movements during sleep, sleep fragmentation, and sleep-wake complaints.

Authors: L Rosenthal; T Roehrs; J Sicklesteel; F Zorick; R Wittig; T Roth
Journal: Sleep Date: 1984 Impact factor: 5.849

9. Periodic movements in sleep and sleep-wake complaint.

Authors: P Saskin; H Moldofsky; F A Lue
Journal: Sleep Date: 1985-12 Impact factor: 5.849

10. Nocturnal myoclonus: treatment efficacy of clonazepam and temazepam.

Authors: M M Mitler; C P Browman; S J Menn; K Gujavarty; R M Timms
Journal: Sleep Date: 1986 Impact factor: 5.849

10 in total

12 in total

10. A Prospective, Randomized, Open-Label Study Comparing the Efficacy and Safety of Clonazepam versus Nortriptyline on Quality of Life in 40+ Years old Women Presenting with Restless Leg Syndrome.

Authors: Vishal R Tandon; Annil Mahajan; Sudhaa Sharma; Vijay Khajuria
Journal: J Midlife Health Date: 2018 Jul-Sep

Double-blind evaluation of clonazepam on periodic leg movements in sleep.

1. Nocturnal myoclonus.

2. Sleep-related periodic myoclonus in patients complaining of insomnia.

3. Periodic leg movements in sleep: effect of clonazepam treatment.

4. [Apropos of some nocturnal myoclonic manifestations. (Symonds' nocturnal myoclonus)].

5. Effect of baclofen on sleep-related periodic leg movements.

6. Descriptive epidemiology of Creutzfeldt-Jakob disease in Chile.

7. Periodic movements in sleep (nocturnal myoclonus): relation to sleep disorders.

8. Periodic movements during sleep, sleep fragmentation, and sleep-wake complaints.

9. Periodic movements in sleep and sleep-wake complaint.

10. Nocturnal myoclonus: treatment efficacy of clonazepam and temazepam.

1. Restless Legs Syndrome.

Review 2. Restless legs syndrome: pathophysiology, clinical presentation and management.

Review 3. Management of restless legs syndrome in patients on dialysis.

4. Recent advances in the diagnosis, genetics and treatment of restless legs syndrome.

5. Restless legs syndrome: a unique case and essentials of diagnosis and treatment.

Review 6. Restless legs and periodic leg movements in sleep syndromes.

Review 7. Update on Restless Legs Syndrome: from Mechanisms to Treatment.

Review 8. Clonazepam for the management of sleep disorders.

9. Treatment of sleep disorders in children.

10. A Prospective, Randomized, Open-Label Study Comparing the Efficacy and Safety of Clonazepam versus Nortriptyline on Quality of Life in 40+ Years old Women Presenting with Restless Leg Syndrome.