Literature DB >> 3437285

Secondary metabolites from Fusarium. Two new modified trichothecenes from Fusarium sporotrichioides MC-72083.

D G Corley1, G E Rottinghaus, M S Tempesta.   

Abstract

Two new, relatively non-toxic, secondary metabolites characterized as 8 alpha- and 8 beta-hydroxysambucoin [1] and [2], isolated from the toxigenic fungus Fusarium sporotrichioides MC-72083 are reported. The structural assignments were established by spectral data with 1H-nmr studies (COSY, dnOes) playing a key role in establishing the stereochemistry in 1 and 2. The isolation of 14 known trichothecenes produced by this fungus is also discussed.

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Year:  1987        PMID： 3437285     DOI： 10.1021/np50053a021

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  4 in total

1.  Cytotoxicity of trichothecene mycotoxins isolated from Fusarium sporotrichioides (MC-72083) and Fusarium sambucinum in baby hamster kidney (BHK-21) cells.

Authors:  L H Senter; D R Sanson; D G Corley; M S Tempesta; A A Rottinghaus; G E Rottinghaus
Journal:  Mycopathologia       Date:  1991-02       Impact factor: 2.574

2.  New modified trichothecenes accumulated in solid culture by mutant strains of Fusarium sporotrichioides.

Authors:  S P McCormick; S L Taylor; R D Plattner; M N Beremand
Journal:  Appl Environ Microbiol       Date:  1989-09       Impact factor: 4.792

3.  Accumulation of Trichothecenes in Liquid Cultures of a Fusarium sporotrichioides Mutant Lacking a Functional Trichothecene C-15 Hydroxylase.

Authors:  S P McCormick; T M Hohn
Journal:  Appl Environ Microbiol       Date:  1997-05       Impact factor: 4.792

Review 4.  Trichothecene biosynthesis in Fusarium species: chemistry, genetics, and significance.

Authors:  A E Desjardins; T M Hohn; S P McCormick
Journal:  Microbiol Rev       Date:  1993-09
  4 in total

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