Literature DB >> 34370284

Ferroptosis: Concepts and Definitions.

Andrés F Flórez1, Hamed Alborzinia2.   

Abstract

Ferroptosis is a newly discovered form of cell death that is rapidly becoming associated to a variety of diseases and explaining their pathological mechanisms. This book addresses new emerging topics in the field of ferroptosis, with special attention to diseases more recently explained through ferroptotic mechanisms, including infectious diseases and neurodegeneration. In this chapter, we will provide the readers with an introduction to the concepts and pathways involved in ferroptosis to further move into a more detailed exposition of the topics advertised in this book. In special, we aim for this book to broaden the perspectives on how ferroptosis is regulated and connected to human diseases and motivate new studies in this emerging field.
© 2021. Springer Nature Switzerland AG.

Entities:  

Keywords:  Apoptosis; Ferroptosis; Hallmarks of ferroptosis; Pyroptosis; TfR1; Transsulfuration

Year:  2021        PMID: 34370284     DOI: 10.1007/978-3-030-62026-4_1

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  30 in total

1.  Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells.

Authors:  Sonam Dolma; Stephen L Lessnick; William C Hahn; Brent R Stockwell
Journal:  Cancer Cell       Date:  2003-03       Impact factor: 31.743

2.  Decreased plasma beta-carotene levels in women with uterine cervical dysplasias and cancer.

Authors:  P R Palan; S L Romney; M Mikhail; J Basu; S H Vermund
Journal:  J Natl Cancer Inst       Date:  1988-05-18       Impact factor: 13.506

3.  FSP1 is a glutathione-independent ferroptosis suppressor.

Authors:  Sebastian Doll; Florencio Porto Freitas; Ron Shah; Maceler Aldrovandi; Milene Costa da Silva; Irina Ingold; Andrea Goya Grocin; Thamara Nishida Xavier da Silva; Elena Panzilius; Christina H Scheel; André Mourão; Katalin Buday; Mami Sato; Jonas Wanninger; Thibaut Vignane; Vaishnavi Mohana; Markus Rehberg; Andrew Flatley; Aloys Schepers; Andreas Kurz; Daniel White; Markus Sauer; Michael Sattler; Edward William Tate; Werner Schmitz; Almut Schulze; Valerie O'Donnell; Bettina Proneth; Grzegorz M Popowicz; Derek A Pratt; José Pedro Friedmann Angeli; Marcus Conrad
Journal:  Nature       Date:  2019-10-21       Impact factor: 49.962

4.  ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.

Authors:  Sebastian Doll; Bettina Proneth; Yulia Y Tyurina; Elena Panzilius; Sho Kobayashi; Irina Ingold; Martin Irmler; Johannes Beckers; Michaela Aichler; Axel Walch; Holger Prokisch; Dietrich Trümbach; Gaowei Mao; Feng Qu; Hulya Bayir; Joachim Füllekrug; Christina H Scheel; Wolfgang Wurst; Joel A Schick; Valerian E Kagan; José Pedro Friedmann Angeli; Marcus Conrad
Journal:  Nat Chem Biol       Date:  2016-11-14       Impact factor: 15.040

Review 5.  Pyroptosis: host cell death and inflammation.

Authors:  Tessa Bergsbaken; Susan L Fink; Brad T Cookson
Journal:  Nat Rev Microbiol       Date:  2009-02       Impact factor: 60.633

Review 6.  Glutathione dysregulation and the etiology and progression of human diseases.

Authors:  Nazzareno Ballatori; Suzanne M Krance; Sylvia Notenboom; Shujie Shi; Kim Tieu; Christine L Hammond
Journal:  Biol Chem       Date:  2009-03       Impact factor: 3.915

7.  Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death.

Authors:  Scott J Dixon; Georg E Winter; Leila S Musavi; Eric D Lee; Berend Snijder; Manuele Rebsamen; Giulio Superti-Furga; Brent R Stockwell
Journal:  ACS Chem Biol       Date:  2015-05-15       Impact factor: 5.100

8.  The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.

Authors:  Kirill Bersuker; Joseph M Hendricks; Zhipeng Li; Leslie Magtanong; Breanna Ford; Peter H Tang; Melissa A Roberts; Bingqi Tong; Thomas J Maimone; Roberto Zoncu; Michael C Bassik; Daniel K Nomura; Scott J Dixon; James A Olzmann
Journal:  Nature       Date:  2019-10-21       Impact factor: 49.962

9.  Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles.

Authors:  John K Eaton; Laura Furst; Richard A Ruberto; Dieter Moosmayer; André Hilpmann; Matthew J Ryan; Katja Zimmermann; Luke L Cai; Michael Niehues; Volker Badock; Anneke Kramm; Sixun Chen; Roman C Hillig; Paul A Clemons; Stefan Gradl; Claire Montagnon; Kiel E Lazarski; Sven Christian; Besnik Bajrami; Roland Neuhaus; Ashley L Eheim; Vasanthi S Viswanathan; Stuart L Schreiber
Journal:  Nat Chem Biol       Date:  2020-03-30       Impact factor: 15.040

10.  Modeling the effects of lipid peroxidation during ferroptosis on membrane properties.

Authors:  Eran Agmon; Jérôme Solon; Patricia Bassereau; Brent R Stockwell
Journal:  Sci Rep       Date:  2018-03-26       Impact factor: 4.379

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  1 in total

1.  MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.

Authors:  Hamed Alborzinia; Andrés F Flórez; Sina Kreth; Lena M Brückner; Umut Yildiz; Moritz Gartlgruber; Dorett I Odoni; Gernot Poschet; Karolina Garbowicz; Chunxuan Shao; Corinna Klein; Jasmin Meier; Petra Zeisberger; Michal Nadler-Holly; Matthias Ziehm; Franziska Paul; Jürgen Burhenne; Emma Bell; Marjan Shaikhkarami; Roberto Würth; Sabine A Stainczyk; Elisa M Wecht; Jochen Kreth; Michael Büttner; Naveed Ishaque; Matthias Schlesner; Barbara Nicke; Carlo Stresemann; María Llamazares-Prada; Jan H Reiling; Matthias Fischer; Ido Amit; Matthias Selbach; Carl Herrmann; Stefan Wölfl; Kai-Oliver Henrich; Thomas Höfer; Andreas Trumpp; Frank Westermann
Journal:  Nat Cancer       Date:  2022-04-28
  1 in total

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