Literature DB >> 34369839

Lack of Premeditation Predicts Aberrant Behaviors Related to Prescription Opioids in Patients with Chronic Pain: A Cross-Sectional Study.

Gabrielle Hettie1, Chinwe Nwaneshiudu1, Maisa S Ziadni1, Beth D Darnall1, Sean C Mackey1, Dokyoung S You1.   

Abstract

OBJECTIVE: In light of the opioid epidemic, there is a need to identify factors that predict aberrant opioid behaviors including misuse and abuse. Impulsivity has been extensively studied in addiction literature, but not in the context of opioid misuse. Hence, this study aimed to identify which of the impulsivity facets (negative urgency, positive urgency, sensation seeking, lack of perseverance, and lack of premeditation) would predict current aberrant opioid-related behaviors in patients with chronic pain.
METHODS: Data were collected through an online survey from patients with chronic pain who visited a tertiary pain clinic. Patients were predominately female (74%), middle aged (M = 55 years), and White/Caucasian (84%). Upon consent, they completed a series of surveys including UPPS-P Impulsive Behavior Scale, the Current Opioid misuse Measure, Pain Catastrophizing Scale, PROMIS-anxiety, depression, and physical function, and a 0-10 numerical pain rating scale. Ordinal regression analyses were conducted to test study hypotheses.
RESULTS: Contrary to expectations, only lack of premeditation predicted higher odds of aberrant opioid-related behaviors in the past 30 days, after controlling for known covariates, and explained 26% of variance. Interestingly, lack of premeditation together with pain catastrophizing as a covariate explained 56% of the variance in aberrant opioid-related behaviors. DISCUSSION: The current study is the first to identify a potential role of lack of premeditation as an impulsivity facet predicting aberrant opioid-related behaviors among patients with chronic pain.

Entities:  

Keywords:  Impulsivity; aberrant opioid-related behaviors; chronic pain; current prescription opioid misuse; lack of premeditation; non-planning impulsivity

Mesh:

Substances:

Year:  2021        PMID: 34369839      PMCID: PMC8928584          DOI: 10.1080/10826084.2021.1958853

Source DB:  PubMed          Journal:  Subst Use Misuse        ISSN: 1082-6084            Impact factor:   2.362


  32 in total

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Journal:  Value Health       Date:  2019-05       Impact factor: 5.725

4.  Craving of prescription opioids in patients with chronic pain: a longitudinal outcomes trial.

Authors:  Ajay D Wasan; Edgar L Ross; Edward Michna; Lori Chibnik; Shelly F Greenfield; Roger D Weiss; Robert N Jamison
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5.  Exploring anxiety sensitivity in the relationship between pain intensity and opioid misuse among opioid-using adults with chronic pain.

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6.  Anxiety sensitivity and pain intensity independently predict opioid misuse and dependence in chronic pain patients.

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7.  Identifying prescription opioid use disorder in primary care: diagnostic characteristics of the Current Opioid Misuse Measure (COMM).

Authors:  Ellen C Meltzer; Denis Rybin; Richard Saitz; Jeffrey H Samet; Sonia L Schwartz; Stephen F Butler; Jane M Liebschutz
Journal:  Pain       Date:  2010-12-21       Impact factor: 6.961

8.  Cross validation of the current opioid misuse measure to monitor chronic pain patients on opioid therapy.

Authors:  Stephen F Butler; Simon H Budman; Gilbert J Fanciullo; Robert N Jamison
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9.  Impulsivity but not sensation seeking is associated with opioid analgesic misuse risk in patients with chronic pain.

Authors:  Elise N Marino; Kristen D Rosen; Antonio Gutierrez; Maxim Eckmann; Somayaji Ramamurthy; Jennifer Sharpe Potter
Journal:  Addict Behav       Date:  2013-02-04       Impact factor: 3.913

10.  The relative contribution of pain and psychological factors to opioid misuse: A 6-month observational study.

Authors:  Marc O Martel; Robert R Edwards; Robert N Jamison
Journal:  Am Psychol       Date:  2020-09
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