Literature DB >> 34369740

Nanoformulations and Highlights of Clinical Studies for Ocular Drug Delivery Systems: An Overview.

Munira M Momin1, Shaikh Darakhshan Afreen2.   

Abstract

Several ocular drug delivery (ODD) systems, like hydrogels, microparticles, nano-emulsions, micro-emulsions, and liposomes have been researched, which can govern the drug release and sustain therapeutic levels for a delayed period in the eye. While new drugs targeting methods to the eye are possible by various nanoparticles. Presently in the market, there are fewer choices and need for novel nano-ocular delivery systems as well as therapies for prolonged delivery to the anterior and posterior eye segments. The primary objective of this article is to summarize current discoveries and proven activities of different nano- and microsystems in ODD. This article also depicts some regulatory updates along with the patents granted to the inventor for their work on ODD. Overall, a thought of how the different forthcoming of nanotechnologies like nanoparticles and nanomedicine can be used to investigate the frontiers of ODD and treatment can be withdrawn by this article.

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Year:  2021        PMID: 34369740     DOI: 10.1615/CritRevTherDrugCarrierSyst.2021035767

Source DB:  PubMed          Journal:  Crit Rev Ther Drug Carrier Syst        ISSN: 0743-4863            Impact factor:   4.889


  4 in total

1.  Preparation and in vitro and in vivo evaluation of an isoliquiritigenin-loaded ophthalmic nanoemulsion for the treatment of corneal neovascularization.

Authors:  Rui Zhang; Jingjing Yang; Qing Luo; Jieran Shi; Haohang Xu; Junjie Zhang
Journal:  Drug Deliv       Date:  2022-12       Impact factor: 6.819

Review 2.  An Update on Novel Ocular Nanosystems with Possible Benefits in the Treatment of Corneal Neovascularization.

Authors:  Chenchen Zhang; Yuan Yin; Jing Zhao; Yanxia Li; Yuanping Wang; Zhaoying Zhang; Lingzhi Niu; Yajuan Zheng
Journal:  Int J Nanomedicine       Date:  2022-10-19

Review 3.  Considerations for Polymers Used in Ocular Drug Delivery.

Authors:  Megan M Allyn; Richard H Luo; Elle B Hellwarth; Katelyn E Swindle-Reilly
Journal:  Front Med (Lausanne)       Date:  2022-01-28

4.  Using Convolutional Neural Network as a Statistical Algorithm to Explore the Therapeutic Effect of Insulin Liposomes on Corneal Inflammation.

Authors:  Yukun Liao; Huiting Jiang; Yangrui Du; Xiaojing Xiong; Yu Zhang; Zhiyu Du
Journal:  Comput Intell Neurosci       Date:  2022-07-31
  4 in total

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