| Literature DB >> 3436851 |
G R Laugel1, H A Dengerink, J W Wright.
Abstract
Ovariectomized rats received intra-arterial infusions of phenylephrine and nicotine. Estrogen treatment for five days prior to these challenges diminished laser Doppler measures of cochlear blood flow (CBF) responses to phenylephrine and blood pressure responses to nicotine. Progesterone enhanced CBF responses to both phenylephrine and nicotine; combined progesterone and estrogen treatment enhanced blood pressure responses to phenylephrine. These results suggest that ovarian steroid-mediated cardiovascular effects may influence cochlear blood flow and potentially hearing functions.Entities:
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Year: 1987 PMID: 3436851 DOI: 10.1016/0378-5955(87)90194-8
Source DB: PubMed Journal: Hear Res ISSN: 0378-5955 Impact factor: 3.208