Literature DB >> 34364786

Harnessing the healing power of love.

Charles L Ford1, Larry J Young2.   

Abstract

A recent paper by Naderi et al. published in eLife shows that pair bonding in monogamous mice is protective against tumor growth, likely via changes in serum factors and cancer cell transcription. We propose that studying the pathway linking social stimuli to cancer cell gene regulation offers a means to identify novel pharmacological targets.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  cancer; drug discovery; marital status; psychosomatic; social bonding; widowhood effect

Mesh：

Year:  2021        PMID： 34364786      PMCID： PMC8605763          DOI： 10.1016/j.molmed.2021.07.010

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   15.272


  10 in total

Review 1.  Therapeutic Implications of Brain-Immune Interactions: Treatment in Translation.

Authors:  Andrew H Miller; Ebrahim Haroon; Jennifer C Felger
Journal:  Neuropsychopharmacology       Date:  2016-08-24       Impact factor: 7.853

2.  Activation of the reward system boosts innate and adaptive immunity.

Authors:  Tamar L Ben-Shaanan; Hilla Azulay-Debby; Tania Dubovik; Elina Starosvetsky; Ben Korin; Maya Schiller; Nathaniel L Green; Yasmin Admon; Fahed Hakim; Shai S Shen-Orr; Asya Rolls
Journal:  Nat Med       Date:  2016-07-04       Impact factor: 53.440

3.  The sympathetic nervous system induces a metastatic switch in primary breast cancer.

Authors:  Erica K Sloan; Saul J Priceman; Benjamin F Cox; Stephanie Yu; Matthew A Pimentel; Veera Tangkanangnukul; Jesusa M G Arevalo; Kouki Morizono; Breanne D W Karanikolas; Lily Wu; Anil K Sood; Steven W Cole
Journal:  Cancer Res       Date:  2010-09-07       Impact factor: 12.701

4.  Life expectancy and active life expectancy by marital status among older U.S. adults: Results from the U.S. Medicare Health Outcome Survey (HOS).

Authors:  Haomiao Jia; Erica I Lubetkin
Journal:  SSM Popul Health       Date:  2020-08-15

5.  Melancholy as a risk factor for cancer: a historical overview.

Authors:  Marianna Karamanou; Elias Tzavellas; Konstantinos Laios; Michalis Koutsilieris; George Androutsos
Journal:  J BUON       Date:  2016 May-Jun       Impact factor: 2.533

6.  The effect of widowhood on mortality by the causes of death of both spouses.

Authors:  Felix Elwert; Nicholas A Christakis
Journal:  Am J Public Health       Date:  2008-05-29       Impact factor: 9.308

Review 7.  Lost connections: Oxytocin and the neural, physiological, and behavioral consequences of disrupted relationships.

Authors:  Tobias T Pohl; Larry J Young; Oliver J Bosch
Journal:  Int J Psychophysiol       Date:  2018-01-09       Impact factor: 2.997

Review 8.  The neural mechanisms and circuitry of the pair bond.

Authors:  Hasse Walum; Larry J Young
Journal:  Nat Rev Neurosci       Date:  2018-11       Impact factor: 34.870

9.  Persistent effects of pair bonding in lung cancer cell growth in monogamous Peromyscus californicus.

Authors:  Asieh Naderi; Elham Soltanmaohammadi; Vimala Kaza; Shayne Barlow; Ioulia Chatzistamou; Hippokratis Kiaris
Journal:  Elife       Date:  2021-05-07       Impact factor: 8.140

10.  Assessment of Modifiable Factors for the Association of Marital Status With Cancer-Specific Survival.

Authors:  Zi-Hang Chen; Kai-Bin Yang; Yuan-Zhe Zhang; Chen-Fei Wu; Dan-Wan Wen; Jia-Wei Lv; Guang-Li Zhu; Xiao-Jing Du; Lei Chen; Guan-Qun Zhou; Qing Liu; Ying Sun; Jun Ma; Cheng Xu; Li Lin
Journal:  JAMA Netw Open       Date:  2021-05-03
  10 in total
  1 in total

Review 1.  Oxytocin, Vasopressin, and Social Behavior: From Neural Circuits to Clinical Opportunities.

Authors:  Nicole Rigney; Geert J de Vries; Aras Petrulis; Larry J Young
Journal:  Endocrinology       Date:  2022-09-01       Impact factor: 5.051
  1 in total

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