Daniel Cuestas1,2,3, John Pedraza4, Hugo Herrera1,2, Adriana Motta1,2, Andrés Cuestas3,5, Yency Forero6, Ricardo Porras1,2, Fernando Urrea7, Dany Galvis7, Ingrid Galvis8, Maria-Alejandra Bernal7, Maria-Victoria Alvarado7, Rosa Bula9, Oscar Velasquez10, Dennys Villalba11, Sergio Lamus7, Gabriel Ariza7, Natalia Bayona12, Ana Gutierrez1,2, Alexandra Segura13, Monica Patiño14, Alejandra Perafan1,2, Santiago Ramirez-Rodriguez12, Mariam Rolon1,2,15. 1. Dermatology Program, Universidad El Bosque, Bogotá, Colombia. 2. Dermatology Service, Hospital Simon Bolivar, Bogotá, Colombia. 3. ESTUDIODERMA®, Bogotá, Colombia. 4. Dermatology Program, Fundacion Universitaria Sanitas, Bogotá, Colombia. 5. Clinical and Enginnering Research-Statistical Analysis, Predicto Artificial Intelligence Techonologies LLC, Austin, TX, USA. 6. Internal Medicine Program, Universidad de La Sabana, Chía, Colombia. 7. Clinical Research, Universidad de La Sabana, Chía, Colombia. 8. Special Training in Radiology, Universidad de La Sabana, Chía, Colombia. 9. Clinical Research, Universidad del Sinú, Cartagena, Colombia. 10. Dermatology Program, Universidad Nacional de Colombia, Bogotá, Colombia. 11. Clinical Research, Universidad El Bosque, Bogotá, Colombia. 12. Clinical Research, Universidad del Rosario, Bogotá, Colombia. 13. Grupo de Investigación en Ciencias Biomédicas UPTC - GICBUPTC, Grupo de Investigación en Medicina Veterinaria y Zootecnia GIDIMEVETZ, Universidad Pedagógica y Tecnológica de Colombia, Tunja, Colombia. 14. Clinical Research, Universidad Pontificia Bolivariana, Medellin, Colombia. 15. Dermatopathology Department, Hospital Simon Bolívar, Bogotá, Colombia.
Abstract
BACKGROUND: Cutaneous myiasis in patients with malignant wounds or skin cancer is a rare and undesirable event with limited epidemiological data. A subregister of reports, lack of education in the population, inadequate empirical treatments, and medical underestimation are components of a public health problem that threatens patients' lives. METHODS: We conducted a systematic review of the literature of cutaneous myiasis associated with malignant wounds and skin cancer, characterizing sociodemographic variables, risk factors, clinical and histological features, and treatment. Additionally, we present a demonstrative case with the adequate taxonomic evaluation. DISCUSSION: Cutaneous myiasis is an underestimated and poorly managed infestation, which can generate severe complications in oncological patients. This is the first systematic review in the literature about this clinical scenario, which provides information to the physician and clinical researcher about the epidemiological gaps and what has been published so far. CONCLUSIONS: Findings from the current review have helped to display the sociodemographic, epidemiological, and clinical behavior of myiasis in skin cancer and malignant wounds. Its contribution to the greater tumor tissue destruction is clear; however, more studies are required. The therapeutic management in these patients is equally clarified.
BACKGROUND:Cutaneous myiasis in patients with malignant wounds or skin cancer is a rare and undesirable event with limited epidemiological data. A subregister of reports, lack of education in the population, inadequate empirical treatments, and medical underestimation are components of a public health problem that threatens patients' lives. METHODS: We conducted a systematic review of the literature of cutaneous myiasis associated with malignant wounds and skin cancer, characterizing sociodemographic variables, risk factors, clinical and histological features, and treatment. Additionally, we present a demonstrative case with the adequate taxonomic evaluation. DISCUSSION: Cutaneous myiasis is an underestimated and poorly managed infestation, which can generate severe complications in oncological patients. This is the first systematic review in the literature about this clinical scenario, which provides information to the physician and clinical researcher about the epidemiological gaps and what has been published so far. CONCLUSIONS: Findings from the current review have helped to display the sociodemographic, epidemiological, and clinical behavior of myiasis in skin cancer and malignant wounds. Its contribution to the greater tumor tissue destruction is clear; however, more studies are required. The therapeutic management in these patients is equally clarified.