Literature DB >> 3436369

The influence of dopamine agonists and antagonists on gastric lesions in mice.

P Sikirić1, I Rotkvić, S Mise, S Krizanac, E Suchanek, M Petek, V Gjuris, J Geber, M Tućan-Foretić, I Udovicić.   

Abstract

The dopamine agonist bromocriptine and L-dopa significantly inhibited whereas dopamine antagonist haloperidol aggravated the gastric lesions induced by pylorus ligation in mice as found earlier for rats. Furthermore, the successful use of a dopamine antagonist alone for the induction of gastric lesions also in mice was demonstrated, since the gastric lesions were induced by a single dose of haloperidol without any additional noxious treatment. Bromocriptine successfully inhibited both the gastric lesion-potentiating as well as the gastric lesion-inducing effect of haloperidol.

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Year:  1987        PMID： 3436369     DOI： 10.1016/0014-2999(87)90525-5

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  5 in total

1.  Salutary and prophylactic effect of pentadecapeptide BPC 157 on acute pancreatitis and concomitant gastroduodenal lesions in rats.

Authors:  P Sikirić; S Seiwerth; Z Grabarević; R Rucman; M Petek; V Jagić; B Turković; I Rotkvić; S Mise; I Zoricić; L Jurina; P Konjevoda; M Hanzevacki; D Ljubanović; J Separović; M Gjurasin; M Bratulić; B Artuković; N Jelovac; G Buljat
Journal:  Dig Dis Sci       Date:  1996-07       Impact factor: 3.199

2.  Pentadecapeptide BPC 157 interactions with adrenergic and dopaminergic systems in mucosal protection in stress.

Authors:  P Sikirić; B Mazul; S Seiwerth; Z Grabarević; R Rucman; M Petek; V Jagić; B Turković; I Rotkvić; S Mise; I Zoricić; L Jurina; P Konjevoda; M Hanzevacki; M Gjurasin; J Separović; D Ljubanović; B Artuković; M Bratulić; M Tisljar; P Miklić; J Sumajstorcić
Journal:  Dig Dis Sci       Date:  1997-03       Impact factor: 3.199

Review 3.  Dopamine in gastrointestinal disease.

Authors:  G B Glavin; S Szabo
Journal:  Dig Dis Sci       Date:  1990-09       Impact factor: 3.199

4.  Monoamine oxidase B inhibition reduces gastric mucosal blood flow, basal acid secretion, and cold water restraint-induced gastric mucosal injury in rats.

Authors:  L P Xing; J Washington; J Seaton; G Kauffman
Journal:  Dig Dis Sci       Date:  1990-01       Impact factor: 3.199

5.  Class side effects: decreased pressure in the lower oesophageal and the pyloric sphincters after the administration of dopamine antagonists, neuroleptics, anti-emetics, L-NAME, pentadecapeptide BPC 157 and L-arginine.

Authors:  Zeljka Belosic Halle; Josipa Vlainic; Domagoj Drmic; Dean Strinic; Kresimir Luetic; Mario Sucic; Maria Medvidovic-Grubisic; Tatjana Pavelic Turudic; Igor Petrovic; Sven Seiwerth; Predrag Sikiric
Journal:  Inflammopharmacology       Date:  2017-05-17       Impact factor: 4.473
  5 in total

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