| Literature DB >> 34361227 |
Syed Mohammed Basheeruddin Asdaq1, Abu Md Ashif Ikbal2, Ram Kumar Sahu3,4, Bedanta Bhattacharjee5, Tirna Paul5, Bhargab Deka5, Santosh Fattepur6, Retno Widyowati3, Joshi Vijaya7, Mohammed Al Mohaini8,9, Abdulkhaliq J Alsalman10, Mohd Imran11, Sreeharsha Nagaraja12,13, Anroop B Nair12, Mahesh Attimarad12, Katharigatta N Venugopala12,14.
Abstract
The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The current emergency necessitates extensive therapy in order to stop the spread of the coronavirus. There are various vaccinations available, but no validated COVID-19 treatments. Since its outbreak, many therapeutics have been tested, including the use of repurposed medications, nucleoside inhibitors, protease inhibitors, broad spectrum antivirals, convalescence plasma therapies, immune-modulators, and monoclonal antibodies. However, these approaches have not yielded any outcomes and are mostly used to alleviate symptoms associated with potentially fatal adverse drug reactions. Nanoparticles, on the other hand, may prove to be an effective treatment for COVID-19. They can be designed to boost the efficacy of currently available antiviral medications or to trigger a rapid immune response against COVID-19. In the last decade, there has been significant progress in nanotechnology. This review focuses on the virus's basic structure, pathogenesis, and current treatment options for COVID-19. This study addresses nanotechnology and its applications in diagnosis, prevention, treatment, and targeted vaccine delivery, laying the groundwork for a successful pandemic fight.Entities:
Keywords: COVID-19; biosensors; nanotechnology; sanitizers; vaccines
Year: 2021 PMID: 34361227 DOI: 10.3390/nano11071841
Source DB: PubMed Journal: Nanomaterials (Basel) ISSN: 2079-4991 Impact factor: 5.076