Literature DB >> 34361227

Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic.

Syed Mohammed Basheeruddin Asdaq1, Abu Md Ashif Ikbal2, Ram Kumar Sahu3,4, Bedanta Bhattacharjee5, Tirna Paul5, Bhargab Deka5, Santosh Fattepur6, Retno Widyowati3, Joshi Vijaya7, Mohammed Al Mohaini8,9, Abdulkhaliq J Alsalman10, Mohd Imran11, Sreeharsha Nagaraja12,13, Anroop B Nair12, Mahesh Attimarad12, Katharigatta N Venugopala12,14.   

Abstract

The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The current emergency necessitates extensive therapy in order to stop the spread of the coronavirus. There are various vaccinations available, but no validated COVID-19 treatments. Since its outbreak, many therapeutics have been tested, including the use of repurposed medications, nucleoside inhibitors, protease inhibitors, broad spectrum antivirals, convalescence plasma therapies, immune-modulators, and monoclonal antibodies. However, these approaches have not yielded any outcomes and are mostly used to alleviate symptoms associated with potentially fatal adverse drug reactions. Nanoparticles, on the other hand, may prove to be an effective treatment for COVID-19. They can be designed to boost the efficacy of currently available antiviral medications or to trigger a rapid immune response against COVID-19. In the last decade, there has been significant progress in nanotechnology. This review focuses on the virus's basic structure, pathogenesis, and current treatment options for COVID-19. This study addresses nanotechnology and its applications in diagnosis, prevention, treatment, and targeted vaccine delivery, laying the groundwork for a successful pandemic fight.

Entities:  

Keywords:  COVID-19; biosensors; nanotechnology; sanitizers; vaccines

Year:  2021        PMID: 34361227     DOI: 10.3390/nano11071841

Source DB:  PubMed          Journal:  Nanomaterials (Basel)        ISSN: 2079-4991            Impact factor:   5.076


  5 in total

Review 1.  Recent Progress on Highly Selective and Sensitive Electrochemical Aptamer-based Sensors.

Authors:  Tianwei Tang; Yinghuan Liu; Ying Jiang
Journal:  Chem Res Chin Univ       Date:  2022-05-05       Impact factor: 2.726

2.  Special Issue "Nanomaterials for Biomedical and Biotechnological Applications".

Authors:  Angelo Ferraro
Journal:  Nanomaterials (Basel)       Date:  2022-06-04       Impact factor: 5.719

Review 3.  Nigella sativa L. and COVID-19: A Glance at The Anti-COVID-19 Chemical Constituents, Clinical Trials, Inventions, and Patent Literature.

Authors:  Mohd Imran; Shah Alam Khan; Mohammed Kanan Alshammari; Saif M Alkhaldi; Fayez Nafea Alshammari; Mehnaz Kamal; Ozair Alam; Syed Mohammed Basheeruddin Asdaq; A Khuzaim Alzahrani; Shahamah Jomah
Journal:  Molecules       Date:  2022-04-25       Impact factor: 4.927

Review 4.  A comprehensive review on efficient approaches for combating coronaviruses.

Authors:  Mahdi Pouresmaieli; Elena Ekrami; Ali Akbari; Negin Noorbakhsh; Negin Borzooee Moghadam; Matin Mamoudifard
Journal:  Biomed Pharmacother       Date:  2021-10-22       Impact factor: 6.529

Review 5.  Potential of Azadirachta indica as a Capping Agent for Antiviral Nanoparticles against SARS-CoV-2.

Authors:  Frank Eric Tatsing Foka; Nanabi Manamela; Steven Maluta Mufamadi; Hazel Tumelo Mufhandu
Journal:  Biomed Res Int       Date:  2022-09-15       Impact factor: 3.246

  5 in total

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