Literature DB >> 34360931

Fatty Acid Synthesis in Glial Cells of the CNS.

Aida V Garcia Corrales1, Mansour Haidar1, Jeroen F J Bogie1, Jerome J A Hendriks1.   

Abstract

n class="Chemical">Fatty acids (n>n class="Chemical">FAs) are of crucial importance for brain homeostasis and neural function. Glia cells support the high demand of FAs that the central nervous system (CNS) needs for its proper functioning. Additionally, FAs can modulate inflammation and direct CNS repair, thereby contributing to brain pathologies such Alzheimer's disease or multiple sclerosis. Intervention strategies targeting FA synthesis in glia represents a potential therapeutic opportunity for several CNS diseases.

Entities:  

Keywords:  CNS repair; central nervous system; fatty acids; glia; neurological disease

Year:  2021        PMID： 34360931     DOI： 10.3390/ijms22158159

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN： 1422-0067            Impact factor:   5.923


  2 in total

1.  Morin, the PPARγ agonist, inhibits Th17 differentiation by limiting fatty acid synthesis in collagen-induced arthritis.

Authors:  Yumeng Miao; Xiaoqian Wu; Xinru Xue; Xingyu Ma; Ling Yang; Xi Zeng; Yuxiao Hu; Yue Dai; Zhifeng Wei
Journal:  Cell Biol Toxicol       Date:  2022-09-19       Impact factor: 6.819

Review 2.  Pathophysiology of Lipid Droplets in Neuroglia.

Authors:  Tina Smolič; Robert Zorec; Nina Vardjan
Journal:  Antioxidants (Basel)       Date:  2021-12-23
  2 in total

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