Literature DB >> 3435898

Lipid peroxidation induced by cyclophosphamide.

M J Berrigan1, R F Struck, H L Gurtoo.   

Abstract

Intraperitoneal administration of a single dose of cyclophosphamide (CP) to rats was found to produce hepatic glutathione depletion and to enhance NADPH-mediated lipid peroxidation in the 15,000 x g supernatant fraction of the liver. These effects were associated with CP in a dose- and a time-dependent manner. The data suggest that the glutathione depletion is, at least in part, responsible for the enhancement in lipid peroxidation induced by CP.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3435898

Source DB:  PubMed          Journal:  Cancer Biochem Biophys        ISSN： 0305-7232


  6 in total

1.  Mitigation of oxidative stress in cyclophosphamide-challenged hepatic tissue by DL-alpha-lipoic acid.

Authors:  Elangovan Selvakumar; Chidambaram Prahalathan; Yenjerla Mythili; Palaninathan Varalakshmi
Journal:  Mol Cell Biochem       Date:  2005-04       Impact factor: 3.396

2.  Prospective Case-Control Study to Evaluate the Role of Glutathione S Transferases (GSTT1 and GSTM1) Gene Deletion in Breast Carcinoma and Its Prognostic Significance.

Authors:  Virinder Kumar Bansal; Karthik Rajan; Arundhati Sharma; Preeti Paliwal; Gaurav Chaubal; Vikas Jindal; Mahesh C Misra; Kiran Kucheria
Journal:  Indian J Surg       Date:  2014-08-05       Impact factor: 0.656

3.  Studies on the cytotoxic, biochemical and anti-carcinogenic potentials of ninhydrin on Ehrlich ascites carcinoma cell-bearing Swiss albino mice.

Authors:  S Qureshi; O A Al-Shabanah; A M Al-Bekairi; M M Al-Harbi; N M Al-Gharably; M Raza
Journal:  Invest New Drugs       Date:  2000-08       Impact factor: 3.850

4.  Evaluation of the genotoxic, cytotoxic, and antitumor properties of Commiphora molmol using normal and Ehrlich ascites carcinoma cell-bearing Swiss albino mice.

Authors:  S Qureshi; M M al-Harbi; M M Ahmed; M Raza; A B Giangreco; A H Shah
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

5.  The Hepatoprotective Effect of Haoqin Qingdan Decoction against Liver Injury Induced by a Chemotherapeutic Drug Cyclophosphamide.

Authors:  Xiaojiang Li; Baole Li; Yingjie Jia
Journal:  Evid Based Complement Alternat Med       Date:  2015-05-26       Impact factor: 2.629

6.  Validation of 1-methyl-2-phenylindole method for estimating lipid peroxidation in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ)Bg (9.).

Authors:  Yasir Hasan Siddique; Smita Jyoti; Falaq Naz; Mohammad Afzal
Journal:  Pharm Methods       Date:  2012-07
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.