Literature DB >> 34358529

Epigenetic Regulation of Apoptosis in Cutaneous T-Cell Lymphoma: Implications for Therapy with Methotrexate, Jak Inhibitors, and Resveratrol.

Minakshi Nihal1, Jianqiang Wu2, Connor J Stonesifer3, Jay Daniels4, Jaehyuk Choi4, Larisa Geskin3, Alain H Rook5, Gary S Wood2.   

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Year:  2021        PMID: 34358529      PMCID: PMC9017049          DOI: 10.1016/j.jid.2021.06.034

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN: 0022-202X            Impact factor:   7.590


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  15 in total

1.  Mutated JAK kinases and deregulated STAT activity are potential therapeutic targets in cutaneous T-cell lymphoma.

Authors:  Cristina Pérez; Julia González-Rincón; Arantza Onaindia; Carmen Almaráz; Nuria García-Díaz; Helena Pisonero; Soraya Curiel-Olmo; Sagrario Gómez; Laura Cereceda; Rebeca Madureira; Mercedes Hospital; Dolores Suárez-Massa; José L Rodriguez-Peralto; Concepción Postigo; Alicia Leon-Castillo; Carmen González-Vela; Nerea Martinez; Pablo Ortiz-Romero; Margarita Sánchez-Beato; Miguel Á Piris; José P Vaqué
Journal:  Haematologica       Date:  2015-08-20       Impact factor: 9.941

2.  Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.

Authors:  Zhen Quan; Yunfeng He; Chunli Luo; Yang Xia; Yan Zhao; Nanjing Liu; Xiaohou Wu
Journal:  Cell Signal       Date:  2017-01-16       Impact factor: 4.315

3.  Reduction of Fas/CD95 promoter methylation, upregulation of Fas protein, and enhancement of sensitivity to apoptosis in cutaneous T-cell lymphoma.

Authors:  Jianqiang Wu; Gary S Wood
Journal:  Arch Dermatol       Date:  2010-12-20

Review 4.  The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas.

Authors:  Rein Willemze; Lorenzo Cerroni; Werner Kempf; Emilio Berti; Fabio Facchetti; Steven H Swerdlow; Elaine S Jaffe
Journal:  Blood       Date:  2019-01-11       Impact factor: 22.113

5.  STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes.

Authors:  Qian Zhang; Hong Y Wang; Anders Woetmann; Puthiyaveettil N Raghunath; Niels Odum; Mariusz A Wasik
Journal:  Blood       Date:  2006-08-01       Impact factor: 22.113

6.  In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.

Authors:  V H Sommer; O J Clemmensen; O Nielsen; M Wasik; P Lovato; C Brender; K W Eriksen; A Woetmann; C G Kaestel; M H Nissen; C Ropke; S Skov; N Ødum
Journal:  Leukemia       Date:  2004-07       Impact factor: 11.528

7.  Critical role for lysine 685 in gene expression mediated by transcription factor unphosphorylated STAT3.

Authors:  Maupali Dasgupta; Hamiyet Unal; Belinda Willard; Jinbo Yang; Sadashiva S Karnik; George R Stark
Journal:  J Biol Chem       Date:  2014-09-12       Impact factor: 5.157

8.  The Janus kinase 2 inhibitor fedratinib inhibits thiamine uptake: a putative mechanism for the onset of Wernicke's encephalopathy.

Authors:  Qiang Zhang; Yan Zhang; Sharon Diamond; Jason Boer; Jennifer J Harris; Yu Li; Mark Rupar; Elham Behshad; Christine Gardiner; Paul Collier; Phillip Liu; Timothy Burn; Richard Wynn; Gregory Hollis; Swamy Yeleswaram
Journal:  Drug Metab Dispos       Date:  2014-07-25       Impact factor: 3.922

9.  Methotrexate Is a JAK/STAT Pathway Inhibitor.

Authors:  Sally Thomas; Katherine H Fisher; John A Snowden; Sarah J Danson; Stephen Brown; Martin P Zeidler
Journal:  PLoS One       Date:  2015-07-01       Impact factor: 3.240

Review 10.  Epigenetic Regulatory Mechanisms Induced by Resveratrol.

Authors:  Guilherme Felipe Santos Fernandes; Gabriel Dalio Bernardes Silva; Aline Renata Pavan; Diego Eidy Chiba; Chung Man Chin; Jean Leandro Dos Santos
Journal:  Nutrients       Date:  2017-11-01       Impact factor: 5.717

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  1 in total

Review 1.  Safety and Danger Considerations of Novel Treatments for Atopic Dermatitis in Context of Primary Cutaneous Lymphomas.

Authors:  Karol Kołkowski; Magdalena Trzeciak; Małgorzata Sokołowska-Wojdyło
Journal:  Int J Mol Sci       Date:  2021-12-13       Impact factor: 5.923

  1 in total

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