Kyusup Lee1, Ji-Hoon Jung2, Myunhee Lee1, Dae-Won Kim1, Mahn-Won Park1, Ik-Jun Choi3, Jae-Hwan Lee4, Jang-Hoon Lee5, Sang-Rok Lee6, Pil-Hyung Lee7, Seung-Whan Lee7, Ki-Dong Yoo8, Kyeong-Ho Yun9, Hyun-Jong Lee10, Sung-Ho Her8. 1. Department of Cardiology, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea. 2. Korea Institute of Toxicology, Daejeon 34114, Korea. 3. Department of Cardiology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon 21431, Korea. 4. Department of Cardiology in Internal Medicine, Chungnam National University Hospital, Daejeon 35015, Korea. 5. Department of Internal Medicine, Kyungpook National University Hospital, Daegu 41944, Korea. 6. Department of Cardiology, Chonbuk National University Hospital, Jeonju 54907, Korea. 7. Asan Medical Center, Department of Cardiology, University of Ulsan College of Medicine, Seoul 05505, Korea. 8. Department of Cardiology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea. 9. Regional Cardiocerebrovascular Center, Department of Cardiovascular Medicine, Wonkwang University Hospital, Iksan 54538, Korea. 10. Department of Internal Medicine, Sejong General Hospital, Bucheon 14754, Korea.
Abstract
Background and Objectives: Data is still limited regarding clinical outcomes of rotational atherectomy (RA) after percutaneous coronary intervention. We sought to evaluate clinical outcomes of RA. Materials and Methods: This multi-center registry enrolled patients who underwent RA during PCI from nine tertiary centers in Korea between January 2010 and October 2019. The primary endpoint was target-vessel failure (TVF; the composite outcome of cardiac death, target-vessel spontaneous myocardial infarction, or target-vessel revascularization). Results: Of 540 patients (583 lesions), the mean patient age was 71.4 ± 0.4 years, 323 patients (59.8%) were men, and 305 patients (56.5%) had diabetes mellitus. Technical success rate was 96.4%. In-hospital major adverse cerebral and cardiac events occurred in 63 cases (10.8%). At 1.5 years, 72 (16.0%) of TVFs were occurred. We evaluated independent predictors of TVF, which included current smoker (hazard ratio (HR), 1.92; 95% confidence interval (CI), 1.17-3.16; p = 0.01), chronic renal disease (HR, 1.87; 95% CI, 1.14-3.08; p = 0.013), history of cerebrovascular attack (HR, 2.14; 95% CI, 1.24-3.68; p = 0.006), left ventricle ejection fraction (HR, 0.98; 95% CI, 0.97-0.999; p = 0.037), and left main disease (HR, 1.94; 95% CI, 1.11-3.37; p = 0.019). Conclusions: From this registry, we demonstrated acceptable success rates, in-hospital and mid-term clinical outcomes of RA in the DES era.
Background and Objectives: Data is still limited regarding clinical outcomes of rotational atherectomy (RA) after percutaneous coronary intervention. We sought to evaluate clinical outcomes of RA. Materials and Methods: This multi-center registry enrolled patients who underwent RA during PCI from nine tertiary centers in Korea between January 2010 and October 2019. The primary endpoint was target-vessel failure (TVF; the composite outcome of cardiac death, target-vessel spontaneous myocardial infarction, or target-vessel revascularization). Results: Of 540 patients (583 lesions), the mean patient age was 71.4 ± 0.4 years, 323 patients (59.8%) were men, and 305 patients (56.5%) had diabetes mellitus. Technical success rate was 96.4%. In-hospital major adverse cerebral and cardiac events occurred in 63 cases (10.8%). At 1.5 years, 72 (16.0%) of TVFs were occurred. We evaluated independent predictors of TVF, which included current smoker (hazard ratio (HR), 1.92; 95% confidence interval (CI), 1.17-3.16; p = 0.01), chronic renal disease (HR, 1.87; 95% CI, 1.14-3.08; p = 0.013), history of cerebrovascular attack (HR, 2.14; 95% CI, 1.24-3.68; p = 0.006), left ventricle ejection fraction (HR, 0.98; 95% CI, 0.97-0.999; p = 0.037), and left main disease (HR, 1.94; 95% CI, 1.11-3.37; p = 0.019). Conclusions: From this registry, we demonstrated acceptable success rates, in-hospital and mid-term clinical outcomes of RA in the DES era.
Authors: Angelo Mastrangelo; Giovanni Monizzi; Stefano Galli; Luca Grancini; Cristina Ferrari; Paolo Olivares; Mattia Chiesa; Giuseppe Calligaris; Franco Fabbiocchi; Piero Montorsi; Antonio L Bartorelli Journal: Front Cardiovasc Med Date: 2022-02-21
Authors: Piotr Rola; Jan Jakub Kulczycki; Adrian Włodarczak; Mateusz Barycki; Szymon Włodarczak; Marek Szudrowicz; Łukasz Furtan; Artur Jastrzębski; Maciej Pęcherzewski; Maciej Lesiak; Adrian Doroszko Journal: Int J Environ Res Public Health Date: 2022-07-25 Impact factor: 4.614