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Literature DB >> 34351571

Inhibition of the Neddylation Pathway Suppresses Enterovirus Replication.

Zhe Zhang¹, Haoran Guo^1,2, Jing Wang¹, Yan Li¹, Yanhang Gao³, Quan Liu⁴, Junqi Niu³, Wei Wei^5,6.

Abstract

Entities: Chemical

Mesh：

Year: 2021 PMID： 34351571 PMCID： PMC8692535 DOI： 10.1007/s12250-021-00427-2

Source DB: PubMed Journal: Virol Sin ISSN： 1995-820X Impact factor: 6.947

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19 in total

Review 1. The life cycle of non-polio enteroviruses and how to target it.

Authors: Jim Baggen; Hendrik Jan Thibaut; Jeroen R P M Strating; Frank J M van Kuppeveld
Journal: Nat Rev Microbiol Date: 2018-06 Impact factor: 60.633

2. The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus.

Authors: Henning Hofmann; Eric C Logue; Nicolin Bloch; Waaqo Daddacha; Sylvie B Polsky; Megan L Schultz; Baek Kim; Nathaniel R Landau
Journal: J Virol Date: 2012-09-12 Impact factor: 5.103

3. Phase I Study of the Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Advanced Solid Tumors.

Authors: John Sarantopoulos; Geoffrey I Shapiro; Roger B Cohen; Jeffrey W Clark; John S Kauh; Glen J Weiss; James M Cleary; Devalingam Mahalingam; Michael D Pickard; Hélène M Faessel; Allison J Berger; Kristine Burke; George Mulligan; Bruce J Dezube; R Donald Harvey
Journal: Clin Cancer Res Date: 2015-09-30 Impact factor: 12.531

4. Severe neonatal parechovirus infection and similarity with enterovirus infection.

Authors: Malgorzata A Verboon-Maciolek; Tannette G Krediet; Leo J Gerards; Linda S de Vries; Floris Groenendaal; Anton M van Loon
Journal: Pediatr Infect Dis J Date: 2008-03 Impact factor: 2.129

5. Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema.

Authors: Shih-Min Wang; Huan-Yao Lei; Kao-Jean Huang; Jing-Ming Wu; Jen-Ren Wang; Chun-Keung Yu; Ih-Jen Su; Ching-Chuan Liu
Journal: J Infect Dis Date: 2003-07-23 Impact factor: 5.226

Inhibition of the Neddylation Pathway Suppresses Enterovirus Replication.

Review 1. The life cycle of non-polio enteroviruses and how to target it.

2. The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus.

3. Phase I Study of the Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Advanced Solid Tumors.

4. Severe neonatal parechovirus infection and similarity with enterovirus infection.

5. Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema.

6. An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells.

Review 7. Protein neddylation: beyond cullin-RING ligases.

Review 8. Flu's cues: Exploiting host post-translational modifications to direct the influenza virus replication cycle.

9. A second open reading frame in human enterovirus determines viral replication in intestinal epithelial cells.

10. Neddylation inhibitor MLN4924 has anti-HBV activity via modulating the ERK-HNF1α-C/EBPα-HNF4α axis.

Review 1. Association Between Neddylation and Immune Response.

2. Neddylation of Enterovirus 71 VP2 Protein Reduces Its Stability and Restricts Viral Replication.