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Literature DB >> 34351568

The Roles of Tetramethylpyrazine During Neurodegenerative Disease.

Abstract

With the aging of the world population, neurodegenerative diseases are considered crippling diseases, which seriously affect the quality of life and are an increasing burden on society and the economy. As a major alkaloid in Ligusticum chuanxiong Hort, tetramethylpyrazine (TMP) plays an increasingly significant role during neurodegenerative diseases, including roles as an anti-inflammatory, antioxidative, antiplatelet citatory poisoning, and anti-inflammation. This review focuses on the latest advances in the roles and mechanisms of action of TMP in neurodegenerative diseases to stimulate new concepts and methods for the prevention and treatment of neurodegenerative diseases.

Entities: Chemical

Keywords: Neurodegenerative disease; Neuroprotection; Tetramethylpyrazine

Mesh：

Substances：

Year: 2021 PMID： 34351568 DOI： 10.1007/s12640-021-00398-y

Source DB: PubMed Journal: Neurotox Res ISSN： 1029-8428 Impact factor: 3.911

48 in total

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Authors: Haiyun Chen; Jie Cao; Ling Zha; Peile Wang; Zheng Liu; Baojian Guo; Gaoxiao Zhang; Yewei Sun; Zaijun Zhang; Yuqiang Wang
Journal: Aging (Albany NY) Date: 2020-07-24 Impact factor: 5.682

9. Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease.

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2 in total

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Journal: Evid Based Complement Alternat Med Date: 2022-04-11 Impact factor: 2.650

2. Therapeutic Effects and Metabolic Spectrum of Traditional Chinese Medicine Hengqing II Prescription on Alzheimer's Disease.

Authors: Shengxi Meng; Shaopeng Li; Huize Chen; Chujun Deng; Zeyu Meng; Yimo Wang
Journal: Evid Based Complement Alternat Med Date: 2022-08-02 Impact factor: 2.650

2 in total