| Literature DB >> 34350497 |
Stein J Janssen1, Peter Kloen2.
Abstract
INTRODUCTION: Salvage of infected tibia and fibula non-union and severe open fractures is challenging and often requires staged treatment. We describe all cases that underwent supercutaneous plating of the leg as external fixation technique and assessed union rate, time to union, rate of infection clearance, and patient-reported outcome measures.Entities:
Keywords: External fixation; External fixator; Frame; LCP; Nonunion; Pseudoartrosis; Supercutaneous plating
Mesh:
Year: 2021 PMID: 34350497 PMCID: PMC9522724 DOI: 10.1007/s00402-021-04104-7
Source DB: PubMed Journal: Arch Orthop Trauma Surg ISSN: 0936-8051 Impact factor: 2.928
Baseline characteristics of patients that underwent supercutaneous plating (n = 19)
| Median (interquartile range) | |
|---|---|
| Age (in years) | 53 (38–63) |
| Time between injury and supercutaneous plating (in days) | 131 (40–884) |
aRheumatoid arthritis, vascular claudication, hypertension, coronary heart disease, psoriasis, hypercholesterolemia, breast carcinoma
Fig. 1(Case 13 in Table 3): This patient was transferred to us from an outside institution 26 days after intramedullary nailing of a low-energy injury grade II open distal cruris fracture. The fracture was mal-reduced and infected (A, B). We removed the nail, performed a thorough debridement, took cultures and applied a metaphyseal locking compression plate 4.5/3.5 mm as external fixator (C–E). Cultures were positive for Staphylococcus aureus for which she was treated with clindamycin. The infection was cleared and union was achieved. The plate was removed after 154 days in the outpatient clinic, and no further surgery was required (F, G)
Individual patient data supercutaneous plate cases
| Nr | Age > 50 years | Sex | Indication | Initial surgery at outside institution | Number of prior surgeries | Mechanism of injury | Fracture type | Time injury to plate (in days) | Time plate in situ (in days) | Plate screw-hole ratio | Number of screws | Plate location | Plate type | Bacterial species cultured | Number of subsequent surgeries | Union | Time to union (in days) | Infection clearance | NRS rest pain | NRS walking pain | PCS | MCS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Yes | Male | Nonunion pilon | No | 1 | High-energy | closed | 28 | 94 | 0.5 | 7 | Med. tibia | Distal med. tibia LCP3.5 | 6 | Yes | 300 | Yes | 5 | 0 | 56 | 59 | |
| 2 | Yes | Female | Nonunion pilon | Yes | 3 | Low-energy | closed | 166 | 134 | 4.0 | 4 | Fibula | 2.7 LCP | 1 | Yes | 129 | Yes | 1 | 8 | 30 | 67 | |
| 3 | No | Female | osteomyelitis | Yes | 3 | High-energy | closed | 884 | 104 | 0.4 | 6 | Med. tibia | 4.5 LCP | None | 1 | n/a | n/a | Yes | – | – | – | – |
| 4 | No | Male | Nonunion cruris | Yes | 4 | High-energy | open 3B | 273 | 183 | 0.4 | 14 | Med. AL. tibia | 2 × 4.5 LCP | 2 | Yes | 183 | Yes | – | – | – | – | |
| 5 | No | Female | Nonunion cruris | Yes | 7 | High-energy | open 1 | 971 | 157 | 0.5 | 9 | Med. tibia | Meta. LCP 4.5/3.5 plate | 2 | No | – | Yes | – | – | – | – | |
| 6 | Yes | Female | acute open pilon | No | 0 | High-energy | open 3A | 0 | 84 | 0.6 | 8 | Med. tibia | Meta. LCP 4.5/3.5 plate | None | 2 | Yes | 84 | n/a | 0 | 0 | 48 | 60 |
| 7 | No | Male | Nonunion pilon | No | 1 | High-energy | closed | 120 | 56 | 0.6 | 6 | Med. tibia | Meta. LCP 4.5/3.5 plate | 3 | Yes | 227 | Yes | 0 | 0 | 62 | 32 | |
| 8 | Yes | Male | Nonunion cruris | Yes | 4 | – | open 1 | 409 | 100 | 0.5 | 7 | Med. tibia | 4.5 LCP | 2 | Yes | 258 | Yes | 0 | 1 | 57 | 43 | |
| 9 | No | Male | Nonunion cruris | Yes | 3 | High-energy | open 2 | 1140 | 477 | 0.4 | 8 | Med. tibia | Meta. LCP 4.5/3.5 plate | 4 | Yes | 477 | Yes | 0 | 1 | 51 | 55 | |
| 10 | Yes | Male | Nonunion cruris | No | 3 | High-energy | open 3A | 131 | 56 | 0.5 | 11 | Med. tibia | Meta. LCP 4.5/3.5 plate | 2 | Yes | 440 | Yes | 0 | 2 | 55 | 56 | |
| 11 | Yes | Male | Nonunion cruris | No | 2 | Crush injury | open 2 | 113 | 101 | 0.5 | 8 | Med. tibia | 4.5 LCP | 1 | Yes | 320 | Yes | – | – | – | – | |
| 12 | Yes | Male | osteomyelitis | Yes | 2 | – | – | 8424 | 40 | 0.3 | 7 | Med. tibia | Meta. LCP 4.5/3.5 plate | 2 | n/a | n/a | Yes | 2 | 3 | 47 | 50 | |
| 13 | Yes | Female | infection cruris | Yes | 2 | Low-energy | open 2 | 26 | 154 | 0.6 | 6 | Med. tibia | Meta. LCP 4.5/3.5 plate | 0 | Yes | 154 | Yes | – | – | – | – | |
| 14 | No | Male | Nonunion cruris | No | 2 | High-energy | open 2 | 40 | 55 | 0.5 | 5 | Med. tibia | Meta. LCP 4.5/3.5 plate | 1 | Yes | 956 | Yes | 4 | 8 | 38 | 28 | |
| 15 | Yes | Male | osteomyelitis | Yes | 4 | High-energy | – | 9140 | 66 | 0.3 | 6 | Med. tibia | Meta. LCP 4.5/3.5 plate | 1 | n/a | n/a | Yes | 1 | 4 | 51 | 61 | |
| 16 | No | Male | acute open cruris | Yes | 0 | High-energy | open 3A | 0 | 2 | 0.4 | 8 | Med. tibia | Meta. LCP 4.5/3.5 plate | None | 1 | Yes | 55 | n/a | 0 | 1 | 56 | 53 |
| 17 | No | Male | Nonunion pilon | Yes | 2 | High-energy | open 2 | 106 | 27 | 0.6 | 9 | Med. tibia | Meta. LCP 4.5/3.5 plate | 3 | Yes | 428 | Yes | 0 | 0 | 59 | 58 | |
| 18 | Yes | Male | Nonunion pilon | No | 5 | Low-energy | closed | 52 | 142 | 0.3 | 6 | Med. Tibia | Meta. LCP 4.5/3.5 plate | 11 | Yes | 774 | Quiescent | 0 | 4 | 41 | 60 | |
| 19 | Yes | Male | Nonunion ankle | Yes | 3 | High-energy | open 3a | 143 | 127 | 0.5 | 5 | Fibula | 3.5 LCP | 2 | No | – | Yes | 1 | 2 | 46 | 61 |
– missing or unknown, n/a not applicable, Med. medial, AL. anterolateral, Meta. Metaphyseal
aNot specified
Surgical characteristics of supercutaneous plating (n = 19)
| Median (interquartile range) | |
|---|---|
| Number of screws | 7 (6–8) |
| Number of screws proximal of fracture/nonunion site | 3 (3–4) |
| Number of screws distal of fracture/nonunion site | 4 (3–4) |
| Plate screw–hole ratio | 0.5 (0.38–0.5) |
| Time supercutaneous plate remained in situ (in days) | 100 (56–142) |
Fig. 2(Case 4 in Table 3): This patient was transferred to us from an outside institution a week after a motorbike accident in which he sustained a bilateral open cruris fractures (right leg grade 3B open fracture, left leg grade 2 open fracture) and an right knee dislocation. Both lower legs were initially stabilized at the outside institution with external fixators (A). A week after the injury we extended the right lower leg external fixator to the femur to achieve stability of the unstable knee, combined with wound debridement and a medial gastrocnemius flap to cover the soft-tissue defect of the right lower leg by the plastic surgeon. Cultures demonstrated Staphylococcus aureus and Pseudomonas aeruginosa for which he was treated with rifampicin, flucloxacillin, and ciprofloxacin. Several debridements, reaming of the intramedullary canal, and exchange of the external fixator ensued due to persistent infection of the right lower leg. We subsequently decided to remove the external fixator and place two broad 4.5 mm locking compression plates as external fixators to improve mobility and again thoroughly debrided the bone leaving gentamycin beats in the intramedullary canal (B, C). The infection cleared, and addition of cancellous iliac crest graft resulted in union. The supercutaneous plates were removed after 183 days in the outpatient clinic. Seven months later, he re-fractured his right leg during a mis-step for which he successfully underwent intramedullary nailing (D–F)