Literature DB >> 3434796

A reversed-phase high-performance liquid chromatographic method for characterization of biosynthetic human growth hormone.

R M Riggin1, G K Dorulla, D J Miner.   

Abstract

An isocratic reversed-phase high-performance liquid chromatographic method for the determination of human growth hormone (HGH) purity is described. This method offers superior resolution of HGH-related substances (e.g., sulfoxide and desamido derivatives) from unmodified HGH when compared to a number of alternative chromatographic and electrophoretic techniques.

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Year:  1987        PMID： 3434796     DOI： 10.1016/0003-2697(87)90152-7

Source DB:  PubMed          Journal:  Anal Biochem        ISSN： 0003-2697            Impact factor:   3.365


  7 in total

1.  Determination of end point of primary drying in freeze-drying process control.

Authors:  Sajal M Patel; Takayuki Doen; Michael J Pikal
Journal:  AAPS PharmSciTech       Date:  2010-01-08       Impact factor: 3.246

2.  Nanofluidic device for continuous multiparameter quality assurance of biologics.

Authors:  Sung Hee Ko; Divya Chandra; Wei Ouyang; Taehong Kwon; Pankaj Karande; Jongyoon Han
Journal:  Nat Nanotechnol       Date:  2017-05-22       Impact factor: 39.213

3.  Separation and characterization of modified variants of recombinant human insulin-like growth factor I derived from a fusion protein secreted from Escherichia coli.

Authors:  G Forsberg; G Palm; A Ekebacke; S Josephson; M Hartmanis
Journal:  Biochem J       Date:  1990-10-15       Impact factor: 3.857

4.  An evaluation of different enzymatic cleavage methods for recombinant fusion proteins, applied on des(1-3)insulin-like growth factor I.

Authors:  G Forsberg; B Baastrup; H Rondahl; E Holmgren; G Pohl; M Hartmanis; M Lake
Journal:  J Protein Chem       Date:  1992-04

5.  Solution stability of the monoclonal antibody-vinca alkaloid conjugate, KS1/4-DAVLB.

Authors:  A Riggin; D Clodfelter; A Maloney; E Rickard; E Massey
Journal:  Pharm Res       Date:  1991-10       Impact factor: 4.200

6.  The effects of formulation variables on the stability of freeze-dried human growth hormone.

Authors:  M J Pikal; K M Dellerman; M L Roy; R M Riggin
Journal:  Pharm Res       Date:  1991-04       Impact factor: 4.200

7.  Improvement in the detection of low concentration protein digests on a MALDI TOF/TOF workstation by reducing alpha-cyano-4-hydroxycinnamic acid adduct ions.

Authors:  Xiangping Zhu; Ioannis A Papayannopoulos
Journal:  J Biomol Tech       Date:  2003-12
  7 in total

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