Literature DB >> 34347144

A rare occurrence of an epithelioid glioblastoma in a pediatric patient: case report and review of the literature.

Timothy Beutler1, Satish Krishnamurthy2, Zulma Tovar-Spinoza2.   

Abstract

Epithelioid glioblastoma is a rare tumor in the pediatric population. We present a case report of a 5-year-old boy found to have a large right frontotemporal epithelioid glioblastoma. The patient was treated with maximal safe resection followed by craniospinal radiation. He has now reached 5-year survival and does not have tumor progression. Given the rarity of epithelioid glioblastoma in the pediatric population, the literature surrounding the diagnosis and treatment options for these tumors is reviewed.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Craniospinal radiation; Epithelioid glioblastoma; Pediatric patient

Mesh:

Year:  2021        PMID: 34347144     DOI: 10.1007/s00381-021-05304-7

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  4 in total

1.  Clinical, radiological, histological and molecular characteristics of paediatric epithelioid glioblastoma.

Authors:  A Broniscer; R G Tatevossian; N D Sabin; P Klimo; J Dalton; R Lee; A Gajjar; D W Ellison
Journal:  Neuropathol Appl Neurobiol       Date:  2014-04       Impact factor: 8.090

Review 2.  The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.

Authors:  David N Louis; Arie Perry; Guido Reifenberger; Andreas von Deimling; Dominique Figarella-Branger; Webster K Cavenee; Hiroko Ohgaki; Otmar D Wiestler; Paul Kleihues; David W Ellison
Journal:  Acta Neuropathol       Date:  2016-05-09       Impact factor: 17.088

3.  Epithelioid versus rhabdoid glioblastomas are distinguished by monosomy 22 and immunohistochemical expression of INI-1 but not claudin 6.

Authors:  Bette Kay Kleinschmidt-DeMasters; Ali H Alassiri; Diane K Birks; Kathy L Newell; Wayne Moore; Kevin O Lillehei
Journal:  Am J Surg Pathol       Date:  2010-03       Impact factor: 6.394

4.  Epithelioid GBMs show a high percentage of BRAF V600E mutation.

Authors:  Bette Kay Kleinschmidt-DeMasters; Dara L Aisner; Diane K Birks; Nicholas K Foreman
Journal:  Am J Surg Pathol       Date:  2013-05       Impact factor: 6.394

  4 in total

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