Literature DB >> 34344996

UPR activator eliminates breast tumours.

Sarah Crunkhorn.   

Abstract

Entities:  

Year:  2021        PMID: 34344996     DOI: 10.1038/d41573-021-00133-4

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


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  1 in total

1.  A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice.

Authors:  Matthew W Boudreau; Darjan Duraki; Lawrence Wang; Chengjian Mao; Ji Eun Kim; Madeline A Henn; Bingtao Tang; Sean W Fanning; Jeffrey Kiefer; Theodore M Tarasow; Elizabeth M Bruckheimer; Ramon Moreno; Spyro Mousses; Geoffrey L Greene; Edward J Roy; Ben Ho Park; Timothy M Fan; Erik R Nelson; Paul J Hergenrother; David J Shapiro
Journal:  Sci Transl Med       Date:  2021-07-21       Impact factor: 17.956

  1 in total

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