Literature DB >> 34343321

Clostridioides difficile Infection in Pediatric Inflammatory Bowel Disease: A Clinician's Dilemma.

Máire A Conrad1,2, Judith R Kelsen1,2.   

Abstract

Clostridioides difficile infection (CDI) in children with inflammatory bowel disease (IBD) can present and manifest differently from the general population with CDI, and it can worsen the underlying disease course. Furthermore, current clinical assays used to test for CDI do not accurately distinguish between true CDI or colonization. This uncertainty leads to difficulty in identifying the etiology and therapy for symptomatic patients with IBD. Improved diagnostic tests, biomarkers, and safe and effective treatment options are greatly needed for this vulnerable population.
© The Author(s) 2021. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Clostridioides difficile infection; fecal microbiota transplant; inflammatory bowel disease; pediatric

Mesh：

Year:  2021        PMID： 34343321      PMCID： PMC8600020          DOI： 10.1093/jpids/piab069

Source DB:  PubMed          Journal:  J Pediatric Infect Dis Soc        ISSN： 2048-7193            Impact factor:   5.235


  43 in total

1.  A hospital-based study of the clinical characteristics of Clostridium difficile infection in children.

Authors:  Jonathan D Crews; Hoonmo L Koo; Zhi-Dong Jiang; Jeffrey R Starke; Herbert L DuPont
Journal:  Pediatr Infect Dis J       Date:  2014-09       Impact factor: 2.129

2.  Clostridioides difficile Infection in Children With Inflammatory Bowel Disease.

Authors:  Abin Chandrakumar; Hussein Zohni; Wael El-Matary
Journal:  Inflamm Bowel Dis       Date:  2020-10-23       Impact factor: 5.325

3.  Intestinal inflammatory biomarkers and outcome in pediatric Clostridium difficile infections.

Authors:  Rana E El Feghaly; Jennifer L Stauber; Phillip I Tarr; David B Haslam
Journal:  J Pediatr       Date:  2013-09-04       Impact factor: 4.406

Review 4.  The risk of inflammatory bowel disease flares after fecal microbiota transplantation: Systematic review and meta-analysis.

Authors:  Taha Qazi; Thelina Amaratunga; Edward L Barnes; Monika Fischer; Zain Kassam; Jessica R Allegretti
Journal:  Gut Microbes       Date:  2017-09-12

5.  Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA).

Authors:  L Clifford McDonald; Dale N Gerding; Stuart Johnson; Johan S Bakken; Karen C Carroll; Susan E Coffin; Erik R Dubberke; Kevin W Garey; Carolyn V Gould; Ciaran Kelly; Vivian Loo; Julia Shaklee Sammons; Thomas J Sandora; Mark H Wilcox
Journal:  Clin Infect Dis       Date:  2018-03-19       Impact factor: 9.079

6.  Diagnosis and Management of Clostridium difficile Infection by Pediatric Infectious Diseases Physicians.

Authors:  Julia Shaklee Sammons; Jeffrey S Gerber; Pranita D Tamma; Thomas J Sandora; Susan E Beekmann; Philip M Polgreen; Adam L Hersh
Journal:  J Pediatric Infect Dis Soc       Date:  2013-10-17       Impact factor: 3.164

7.  Decreased Fecal Bacterial Diversity and Altered Microbiome in Children Colonized With Clostridium difficile.

Authors:  Lea Ann Chen; Suchitra K Hourigan; Zoya Grigoryan; Zhan Gao; Jose C Clemente; Jai Ram Rideout; Sankar Chirumamilla; Shervin Rabidazeh; Shehzad Saeed; Charles O Elson; Maria Oliva-Hemker; Martin J Blaser; Cynthia L Sears
Journal:  J Pediatr Gastroenterol Nutr       Date:  2019-04       Impact factor: 2.839

8.  Prevalence of Inflammatory Bowel Disease in Pediatric and Adult Populations: Recent Estimates From Large National Databases in the United States, 2007-2016.

Authors:  Yizhou Ye; Sudhakar Manne; William R Treem; Dimitri Bennett
Journal:  Inflamm Bowel Dis       Date:  2020-03-04       Impact factor: 5.325

9.  Drug-Resistant E. coli Bacteremia Transmitted by Fecal Microbiota Transplant.

Authors:  Zachariah DeFilipp; Patricia P Bloom; Mariam Torres Soto; Michael K Mansour; Mohamad R A Sater; Miriam H Huntley; Sarah Turbett; Raymond T Chung; Yi-Bin Chen; Elizabeth L Hohmann
Journal:  N Engl J Med       Date:  2019-10-30       Impact factor: 91.245

Review 10.  Clostridium difficile infection in children with inflammatory bowel disease: current evidence.

Authors:  Aleksandra Banaszkiewicz; Hanna Pituch
Journal:  Curr Pharm Des       Date:  2014       Impact factor: 3.116
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