Literature DB >> 34342928

Prostate interventions in patients with mild haemophilia: Safe and feasible.

Benoit Mesnard1, Nicolas Drillaud2, Marianne Sigaud2, Gabriella Hakim3, Samuel Chelly4, Catherine Ternisien2, Marc Fouassier2, Ismaël Chelghaf1, Stéphane De Vergie1, Marie-Aimée Perrouin Verbe1, Jérôme Rigaud1, Arthur David5, Marc Trossaërt2, Julien Branchereau1,3,6.   

Abstract

INTRODUCTION: To date, there is no specific recommendation or evaluation of the morbidity of prostate surgery in patients with haemophilia (PWH) although this surgery is common and at high risk of bleeding. AIM: To assess the post-operative morbidity of benign prostate hyperplasia (BPH) surgeries and of oncological prostate interventions in patients with mild haemophilia A or B.
METHODS: We performed a monocentre, epidemiological, in real life study. Data were collected between 1 January, 1997 and 1 September, 2020 and focused on prostate biopsy, radical prostatectomy, prostate radiotherapy, simple prostatectomy, transurethral resection of prostate (TURP) and laser-vaporisation in patients with mild haemophilia A or B.
RESULTS: Between 1 January, 1997 and 1 September, 2020, 51 interventions were performed on 30 patients with mild haemophilia. Haemophilia A represented 93.33% of the population and haemophilia B 6.67%. For prostate biopsies (n = 24), median length of hospitalisation was 4 days and only one patient needed a blood transfusion. No patient needed re-admission. For prostatectomy (n = 10), one patient presented with intra-operative and post-operative bleeding. Two patients required re-admission. The other patients did not present any significant haemorrhagic symptoms. For radiotherapy (n = 4), two patients presented a grade II complication (radiocystitis and radiorectitis). For BPH surgeries, during hospitalisation, laser-vaporisation (n = 5) was less haemorrhagic than TURP (n = 5) but after hospital discharge, 60% of patients presented a haemorrhagic complication with two readmissions and one surgical re-explorations.
CONCLUSION: Performed in a specialised centre, prostate surgeries and interventions in patients with mild haemophilia is feasible with acceptable morbidity.
© 2021 John Wiley & Sons Ltd.

Entities:  

Keywords:  biopsy; haemophilia A; haemophilia B; laser therapy; prostate; prostatectomy; transurethral resection of prostate

Year:  2021        PMID: 34342928     DOI: 10.1111/hae.14388

Source DB:  PubMed          Journal:  Haemophilia        ISSN: 1351-8216            Impact factor:   4.287


  1 in total

1.  Prostatic artery embolization in men with severe hemophilia a: a case report of two patients.

Authors:  Petra Svarc; Peter Kampmann; Lars Lönn; Martin Andreas Røder
Journal:  CVIR Endovasc       Date:  2022-04-21
  1 in total

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