| Literature DB >> 34334841 |
Emanuel Javier Ferreyra1, Matthieu Jonckheere1, Juan Pablo Pinasco2,3.
Abstract
We consider an SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of optimal controls for the limiting equations formulated in the framework of game theory, both in the centralized and decentralized setting. We show how the characteristics of the graph (degree distribution) influence the vaccination efficiency for optimal strategies, and we compute the limiting final size of the epidemic depending on the degree distribution of the graph and the parameters of infection, recovery and vaccination. We also present several simulations for two types of vaccination, showing how the optimal controls allow to decrease the number of infections and underlining the crucial role of the network characteristics in the propagation of the disease and the vaccination program.Entities:
Keywords: Configuration model; Epidemic; Optimal control; SIR-V
Year: 2021 PMID: 34334841 PMCID: PMC8308122 DOI: 10.1007/s00245-021-09810-7
Source DB: PubMed Journal: Appl Math Optim ISSN: 0095-4616 Impact factor: 3.582