Literature DB >> 34333987

Piezo1-Mediated Mechanotransduction Promotes Cardiac Hypertrophy by Impairing Calcium Homeostasis to Activate Calpain/Calcineurin Signaling.

Yuhao Zhang1, Sheng-An Su1, Wudi Li1, Yuankun Ma1, Jian Shen1, Yaping Wang2, Yimin Shen1, Jian Chen1, Yongli Ji1, Yao Xie1, Hong Ma1, Meixiang Xiang1.   

Abstract

[Figure: see text].

Entities:  

Keywords:  calcineurin; calpain; fibrosis; homeostasis; mechanotransduction

Mesh:

Substances:

Year:  2021        PMID: 34333987     DOI: 10.1161/HYPERTENSIONAHA.121.17177

Source DB:  PubMed          Journal:  Hypertension        ISSN: 0194-911X            Impact factor:   10.190


  11 in total

Review 1.  Calpains as Potential Therapeutic Targets for Myocardial Hypertrophy.

Authors:  David Aluja; Sara Delgado-Tomás; Marisol Ruiz-Meana; José A Barrabés; Javier Inserte
Journal:  Int J Mol Sci       Date:  2022-04-07       Impact factor: 6.208

2.  Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice.

Authors:  Fiona Bartoli; Elizabeth L Evans; Nicola M Blythe; Leander Stewart; Eulashini Chuntharpursat-Bon; Marjolaine Debant; Katie E Musialowski; Laeticia Lichtenstein; Gregory Parsonage; T Simon Futers; Neil A Turner; David J Beech
Journal:  Cells       Date:  2022-04-02       Impact factor: 6.600

3.  Proteomic Analysis of the Role of the Adenylyl Cyclase-cAMP Pathway in Red Blood Cell Mechanical Responses.

Authors:  Elif Ugurel; Evrim Goksel; Neslihan Cilek; Elif Kaga; Ozlem Yalcin
Journal:  Cells       Date:  2022-04-06       Impact factor: 6.600

4.  Mechanosensitive Piezo1 channels mediate renal fibrosis.

Authors:  Xiaoduo Zhao; Yonglun Kong; Baien Liang; Jinhai Xu; Yu Lin; Nan Zhou; Jing Li; Bin Jiang; Jianding Cheng; Chunling Li; Weidong Wang
Journal:  JCI Insight       Date:  2022-04-08

Review 5.  The State of the Art of Piezo1 Channels in Skeletal Muscle Regeneration.

Authors:  Annalisa Bernareggi; Alessandra Bosutti; Gabriele Massaria; Rashid Giniatullin; Tarja Malm; Marina Sciancalepore; Paola Lorenzon
Journal:  Int J Mol Sci       Date:  2022-06-14       Impact factor: 6.208

Review 6.  Piezo1 Channel as a Potential Target for Hindering Cardiac Fibrotic Remodeling.

Authors:  Nicoletta Braidotti; Suet Nee Chen; Carlin S Long; Dan Cojoc; Orfeo Sbaizero
Journal:  Int J Mol Sci       Date:  2022-07-22       Impact factor: 6.208

7.  MicroRNA-194 inhibits isoproterenol-induced chronic cardiac hypertrophy via targeting CnA/NFATc2 signaling in H9c2 cells.

Authors:  Jian Wang; Yucheng An; Jun Lin; Gang Tang
Journal:  Ann Transl Med       Date:  2022-07

8.  N-Acetylcysteine, an ROS Inhibitor, Alleviates the Pathophysiology of Hyperthyroidism-Induced Cardiomyopathy via the ROS/Ca2+ Pathway.

Authors:  Mengni Bao; Xiumeng Hua; Han Mo; Zhe Sun; Bo Xu; Xiao Chen; Mengda Xu; Xinjie Xu; Jiangping Song
Journal:  Biomolecules       Date:  2022-08-29

Review 9.  Mechanosensitive Ion Channel PIEZO1 Signaling in the Hall-Marks of Cancer: Structure and Functions.

Authors:  Fuqiang Zhao; Lei Zhang; Mankun Wei; Wei Duan; Shourong Wu; Vivi Kasim
Journal:  Cancers (Basel)       Date:  2022-10-10       Impact factor: 6.575

Review 10.  Heat Shock Protein 90 as Therapeutic Target for CVDs and Heart Ageing.

Authors:  Siarhei A Dabravolski; Vasily N Sukhorukov; Vladislav A Kalmykov; Nikolay A Orekhov; Andrey V Grechko; Alexander N Orekhov
Journal:  Int J Mol Sci       Date:  2022-01-07       Impact factor: 5.923

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