| Literature DB >> 34328384 |
Evagelia Chantzara1, Nikolaos Xenidis2, Galatea Kallergi3, Vassilis Georgoulias4, Athanasios Kotsakis1,5.
Abstract
Introduction : Despite advances in diagnostic and therapeutic techniques breast cancer is still associated with significant morbidity and mortality. CTCs play a crucial role in the metastatic process, which is the main cause of death in BC patients.Areas covered : This review discusses the prognostic and predictive value of CTCs and their prospective in management of BC patients.Expert opinion : The analysis of CTCs through improved technologies offers a new insight into the metastatic cascade. Assessment of the number and molecular profile of CTCs holds great promises for disease monitoring and therapeutic decisions. However, more research is needed until they can be used in therapeutic decisions in clinical practice.Entities:
Keywords: Breast cancer; biomarkers; circulating tumor cells; metastatic cascade; prognosis
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Year: 2021 PMID： 34328384 DOI： 10.1080/14737159.2021.1962710
Source DB: PubMed Journal: Expert Rev Mol Diagn ISSN： 1473-7159 Impact factor: 5.225