| Literature DB >> 34327049 |
Olusola Jumoke Daramola1,2,3, Stephen Osasan4, Hebah Ali5,6, Perpetua Emeagi7.
Abstract
The properties of hematopoietic stem and progenitor cells (HSPCs), including self-renewal and pluripotency, have been extensively studied. These features have been explored in the management of several haematological disorders and malignancies. Although their role as precursors of innate immune cells is well understood, little is known about their direct participation in host immune response. In this review, we explicate the direct role of HSPCs in the host immune response and highlight therapeutic options for the infectious disease burden that is currently ravaging the world, including COVID-19. AJSCEntities:
Keywords: Hematopoietic; haematopoiesis; immune; progenitor cells; stem cells
Year: 2021 PMID: 34327049 PMCID: PMC8310832
Source DB: PubMed Journal: Am J Stem Cells ISSN: 2160-4150