| Literature DB >> 34325682 |
Abstract
Natural killer (NK) cells participate in cancer immunosurveillance and cancer immunotherapy. Live cell imaging of cancer cells targeted by NK cells, published today in BMC Biology by Zhu et al., reveals a remarkable diversity of programmed cell death pathways induced in individual cells. Pathway choice depends on the state of the target cell actin cytoskeleton and a novel death pathway, granzyme-induced necroptosis, could be of broad importance in cancer immunotherapy.Entities:
Year: 2021 PMID: 34325682 DOI: 10.1186/s12915-021-01092-3
Source DB: PubMed Journal: BMC Biol ISSN: 1741-7007 Impact factor: 7.431