Literature DB >> 34325184

Changes in characteristics of drug overdose death trends during the COVID-19 pandemic.

Catherine DiGennaro1, Gian-Gabriel P Garcia1, Erin J Stringfellow1, Sarah Wakeman1, Mohammad S Jalali2.   

Abstract

BACKGROUND: Reports analyzing drug overdose (OD) mortality data during the COVID-19 pandemic are limited. Outcomes across states are heterogenous, necessitating assessments of associations between COVID-19 and OD deaths on a state-by-state level. This report aims to analyze trends in OD deaths in Massachusetts during COVID-19.
METHODS: Analyzing 3,924 death records, we characterize opioid-, cocaine-, and amphetamine-involved OD mortality and substance co-presence trends from March 24-November 8 in 2020 as compared to 2018 and 2019.
RESULTS: OD deaths involving amphetamines increased by 85% from 2019 to 2020 (61 vs. 113; P<0.001) but were steady from 2018 to 2019. Heroin's presence continued to decrease (341 in 2018, 247 in 2019, 157 in 2020; P<0.001); however, fentanyl was present in more than 85% of all OD deaths across all periods. Among OD deaths, alcohol involvement consistently increased, present in 250 deaths in 2018, 299 in 2019 (P=0.02), and 350 in 2020 (P=0.04). In 2019, 78% of OD decedents were White and 7% were Black, versus 73% and 10% in 2020 (P=0.02).
CONCLUSION: Increased deaths involving stimulants, alcohol, and fentanyl reflect concerning trends in the era of COVID-19. Rising OD death rates among Black residents underscore that interventions focused on racial equity are necessary.
Copyright © 2021 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Alcohol; COVID-19; Fentanyl; Opioids; Overdose death; Stimulants

Mesh:

Substances:

Year:  2021        PMID: 34325184     DOI: 10.1016/j.drugpo.2021.103392

Source DB:  PubMed          Journal:  Int J Drug Policy        ISSN: 0955-3959


  13 in total

1.  A Systematic Review of Simulation Models to Track and Address the Opioid Crisis.

Authors:  Magdalena Cerdá; Mohammad S Jalali; Ava D Hamilton; Catherine DiGennaro; Ayaz Hyder; Julian Santaella-Tenorio; Navdep Kaur; Christina Wang; Katherine M Keyes
Journal:  Epidemiol Rev       Date:  2022-01-14       Impact factor: 6.222

2.  Evaluating disparities in prescribing of naloxone after emergency department treatment of opioid overdose.

Authors:  Scott G Weiner; Aleta D Carroll; Nicholas M Brisbon; Claudia P Rodriguez; Charles Covahey; Erin J Stringfellow; Catherine DiGennaro; Mohammad S Jalali; Sarah E Wakeman
Journal:  J Subst Abuse Treat       Date:  2022-04-30

3.  Comparison of Characteristics of Deaths From Drug Overdose Before vs During the COVID-19 Pandemic in Rhode Island.

Authors:  Alexandria Macmadu; Sivakumar Batthala; Annice M Correia Gabel; Marti Rosenberg; Rik Ganguly; Jesse L Yedinak; Benjamin D Hallowell; Rachel P Scagos; Elizabeth A Samuels; Magdalena Cerdá; Kimberly Paull; Brandon D L Marshall
Journal:  JAMA Netw Open       Date:  2021-09-01

4.  Opioid overdose decedent characteristics during COVID-19.

Authors:  Gian-Gabriel P Garcia; Erin J Stringfellow; Catherine DiGennaro; Nicole Poellinger; Jaden Wood; Sarah Wakeman; Mohammad S Jalali
Journal:  Ann Med       Date:  2022-12       Impact factor: 5.348

Review 5.  Unique Pharmacology, Brain Dysfunction, and Therapeutic Advancements for Fentanyl Misuse and Abuse.

Authors:  Ying Han; Lu Cao; Kai Yuan; Jie Shi; Wei Yan; Lin Lu
Journal:  Neurosci Bull       Date:  2022-05-15       Impact factor: 5.271

6.  Racial Disparities in Opioid Overdose Deaths in Massachusetts.

Authors:  Che-Yi Liao; Gian-Gabriel P Garcia; Catherine DiGennaro; Mohammad S Jalali
Journal:  JAMA Netw Open       Date:  2022-04-01

Review 7.  Drugs of Abuse and Their Impact on Viral Pathogenesis.

Authors:  Jason T Blackard; Kenneth E Sherman
Journal:  Viruses       Date:  2021-11-29       Impact factor: 5.048

8.  Impact of the COVID-19 Pandemic on Opioid Overdose Deaths: a Spatiotemporal Analysis.

Authors:  Rina Ghose; Amir M Forati; John R Mantsch
Journal:  J Urban Health       Date:  2022-02-18       Impact factor: 5.801

9.  Navigating intersecting public health crises: a qualitative study of people with opioid use disorders' experiences during the COVID-19 pandemic.

Authors:  Dennis P Watson; Monte D Staton; Christine E Grella; Christy K Scott; Michael L Dennis
Journal:  Subst Abuse Treat Prev Policy       Date:  2022-03-18

10.  The impact of an integrated safer use space and safer supply program on non-fatal overdose among emergency shelter residents during a COVID-19 outbreak: a case study.

Authors:  Brendan Lew; Claire Bodkin; Robin Lennox; Timothy O'Shea; Gillian Wiwcharuk; Suzanne Turner
Journal:  Harm Reduct J       Date:  2022-03-21
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