Literature DB >> 3432172

A cumulative dose comparison between salbutamol and fenoterol metered dose aerosols in asthmatic patients.

D Bellamy1, A Penketh.   

Abstract

The potency and side effects of salbutamol and fenoterol inhalers have been compared in 8 asthmatic patients using a dose response curve. There was no significant difference in the absolute or percentage increase in FEV1 with the two treatments, but fenoterol caused a significantly greater (P less than 0.01) increase in heart rate than did salbutamol. A greater degree of bronchodilatation was observed with increased doses and we suggest that regular higher doses may provide better bronchodilatation and control of asthma in selected patients.

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Year:  1987        PMID： 3432172      PMCID： PMC2428318          DOI： 10.1136/pgmj.63.740.459

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  7 in total

1.  Comparison of the bronchodilator and cardiac effects of hydroxyphenylorciprenaline and orciprenaline.

Authors:  J Beardshaw; L MacLean; M Chan-Yeung
Journal:  Chest       Date:  1974-05       Impact factor: 9.410

2.  Ventilatory results and side-effects of salbutamol given by different routes in coalminers with reversible broncho-obstruction.

Authors:  A Minette
Journal:  Postgrad Med J       Date:  1971-03       Impact factor: 2.401

3.  Clinical assessment of bronchodilator drugs delivered by aerosol.

Authors:  G M Shenfield; J W Paterson
Journal:  Thorax       Date:  1973-03       Impact factor: 9.139

4.  Assessment of optimum dose of inhaled terbutaline in patients with chronic asthma: the use of simple, cumulative dose-response curves.

Authors:  J G Prior; G M Cochrane
Journal:  Br J Dis Chest       Date:  1982-07

5.  High-dose inhaled terbutaline in the management of chronic severe asthma: comparison of wet nebulisation and tube-spacer delivery.

Authors:  J G Prior; R V Nowell; G M Cochrane
Journal:  Thorax       Date:  1982-04       Impact factor: 9.139

6.  Dose-response study of inhaled salbutamol powder in chronic airflow obstruction.

Authors:  P A Corris; E Neville; S Nariman; G J Gibson
Journal:  Thorax       Date:  1983-04       Impact factor: 9.139

7.  A comparative double-blind study of the bronchodilator effects and side effects of inhaled fenoterol and terbutaline administered in equipotent doses.

Authors:  B J Gray; M H Frame; J F Costello
Journal:  Br J Dis Chest       Date:  1982-10
  7 in total

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