Literature DB >> 34321541

Simplifying functional network representation and interpretation through causality clustering.

Massimiliano Zanin1.   

Abstract

Functional networks, i.e. networks representing the interactions between the elements of a complex system and reconstructed from the observed elements' dynamics, are becoming a fundamental tool to unravel the structures created by the movement of information in systems like the human brain. They also present drawbacks, one of the most important being the inherent difficulty in representing and interpreting the resulting structures for large number of nodes and links. I here propose a causality clustering approach, based on grouping nodes into clusters according to their similarity in the overall information dynamics, the latter one being measured by a causality metric. The whole system can then arbitrarily be simplified, with nodes being grouped in e.g. sources, brokers and sinks of information. The advantages and limitations of the proposed approach are discussed using a set of synthetic and real-world data sets, the latter ones representing two neuroscience and technological problems.
© 2021. The Author(s).

Entities:  

Year:  2021        PMID: 34321541     DOI: 10.1038/s41598-021-94797-y

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  22 in total

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Journal:  Nature       Date:  2001-03-08       Impact factor: 49.962

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Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-23       Impact factor: 11.205

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Authors:  Steven L Bressler; Anil K Seth
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4.  Granger causality analysis in neuroscience and neuroimaging.

Authors:  Anil K Seth; Adam B Barrett; Lionel Barnett
Journal:  J Neurosci       Date:  2015-02-25       Impact factor: 6.167

5.  A study of problems encountered in Granger causality analysis from a neuroscience perspective.

Authors:  Patrick A Stokes; Patrick L Purdon
Journal:  Proc Natl Acad Sci U S A       Date:  2017-08-04       Impact factor: 11.205

Review 6.  A review of causal inference for biomedical informatics.

Authors:  Samantha Kleinberg; George Hripcsak
Journal:  J Biomed Inform       Date:  2011-07-14       Impact factor: 6.317

Review 7.  Complex brain networks: graph theoretical analysis of structural and functional systems.

Authors:  Ed Bullmore; Olaf Sporns
Journal:  Nat Rev Neurosci       Date:  2009-02-04       Impact factor: 34.870

Review 8.  Structure and function of complex brain networks.

Authors:  Olaf Sporns
Journal:  Dialogues Clin Neurosci       Date:  2013-09       Impact factor: 5.986

9.  The reproducibility of research and the misinterpretation of p-values.

Authors:  David Colquhoun
Journal:  R Soc Open Sci       Date:  2017-12-06       Impact factor: 2.963

10.  Assessing functional propagation patterns in COVID-19.

Authors:  Massimiliano Zanin; David Papo
Journal:  Chaos Solitons Fractals       Date:  2020-06-12       Impact factor: 5.944

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