Literature DB >> 34318214

Commentary: Closing the gap on bicuspid aortic valve repair.

Keyan Mobli1, Abe DeAnda1.   

Abstract

Entities:  

Year:  2021        PMID: 34318214      PMCID: PMC8311453          DOI: 10.1016/j.xjtc.2021.01.004

Source DB:  PubMed          Journal:  JTCVS Tech        ISSN: 2666-2507


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Summary of the clinical approach to a regurgitant bicuspid aorta valve. Preservation of the aortic valve via repair may be technically challenging, but an understanding of the anatomy, geometry, and mechanisms of insufficiency aids successful repair. See Article page 83. The evolution of mitral valve surgery has progressed from complete replacement to replacement with preservation of the subvalvular apparatus to repair. Complementing this evolution was a detailed understanding of the anatomy and function of all components of the valve and subvalvular mechanism. There should be little doubt that one could have been achieved without the other. We are now following a similar pathway with the aortic valve and the functional aortic annulus. Although not a procedure adopted by all surgeons, preservation of the aortic valve either de novo or as part of a valve-sparing root replacement has been well described for the trileaflet aortic valve (Figure 1). The bicuspid aortic valve (BAV) adds an additional layer to the challenge of repairing the aortic valve, and repair strategies have been developed, evaluated, and championed by centers of excellence, most notably our friends in Belgium.
Figure 1

El Khoury functional classification of aortic insufficiency (AI). FAA, Functional aortic annulus; STJ, sinotubular junction; SCA, subcommissural annuloplasty.

El Khoury functional classification of aortic insufficiency (AI). FAA, Functional aortic annulus; STJ, sinotubular junction; SCA, subcommissural annuloplasty. In this invited review, Jahanyar and colleagues use their extensive experience with >1000 aortic valve repairs to classify the BAV with an anatomic scheme that combines the Sievers classification with 3 phenotypes determined by the commissural angulation. This understanding of the variations in orientation of the commissure and angulation, as well as an appreciation of the differences in a functional aortic annulus, has important implications for a confident repair. In their analysis of their institutional experience, the authors appreciate that regardless of the Sievers classification, there always appears to be some level of prolapse of the fused cusps, with the caveat that bileaflet prolapse can occur in the symmetric phenotype. This finding is somewhat at odds with a scheme from the same institution that classifies aortic insufficiency as type I (aortic dilatation), type II (cusp prolapse), or type III (restrictive), although overlap is frequent. After an extensive preoperative and intraoperative evaluation of the valve geometry, Jahanyar and colleagues present their algorithm and approach for repair. We have attempted to summarize their described approach (Figure 2). As the authors note, the main objectives are to correct the prolapse and stabilize the annulus. Using the commissural orientation approach, the first objective is achieved with symmetrization of the commissures, because this maximizes the cusp tissue available for coaptation. The cusps can then be repaired, typically with plication. The second objective is stabilizing the annulus. There are several approaches to stabilizing the annulus, including partial and complete annuloplasty repair, and if type I insufficiency is part of the etiology, then valve-sparing root replacement might be necessary to deal with the aortopathy as well as to fixate the annulus.
Figure 2

Summary of the clinical approach to a regurgitant bicuspid aorta valve.

Summary of the clinical approach to a regurgitant bicuspid aorta valve. The group at Cliniques Universitaires Saint-Luc has been repairing aortic valves since the 1990s, and their contributions to our understanding of the anatomy and function of the aortic valve and associated components have been invaluable. The commissural reorientation approach to the BAV will add another approach to our options. These procedures are technically challenging requiring a deep understanding of the related anatomy, and currently have unknown durability, predictable repairability, and reproducibility. This mirrors what was said decades ago regarding mitral valve repair.
  5 in total

1.  A classification system for the bicuspid aortic valve from 304 surgical specimens.

Authors:  Hans-H Sievers; Claudia Schmidtke
Journal:  J Thorac Cardiovasc Surg       Date:  2007-05       Impact factor: 5.209

2.  Repair-oriented classification of aortic insufficiency: impact on surgical techniques and clinical outcomes.

Authors:  Munir Boodhwani; Laurent de Kerchove; David Glineur; Alain Poncelet; Jean Rubay; Parla Astarci; Robert Verhelst; Philippe Noirhomme; Gébrine El Khoury
Journal:  J Thorac Cardiovasc Surg       Date:  2008-12-27       Impact factor: 5.209

3.  Repair of bicuspid aortic valves in patients with aortic regurgitation.

Authors:  Gébrine El Khoury; Jean-Louis Vanoverschelde; David Glineur; Frédéric Pierard; Robert R Verhelst; Jean Rubay; Jean-Christophe Funken; Christine Watremez; Parla Astarci; Valérie Lacroix; Alain Poncelet; Philippe Noirhomme
Journal:  Circulation       Date:  2006-07-04       Impact factor: 29.690

4.  Cusp prolapse repair in trileaflet aortic valves: free margin plication and free margin resuspension techniques.

Authors:  Laurent de Kerchove; Munir Boodhwani; David Glineur; Alain Poncelet; Jean Rubay; Christine Watremez; Jean-Louis Vanoverschelde; Philippe Noirhomme; Gébrine El Khoury
Journal:  Ann Thorac Surg       Date:  2009-08       Impact factor: 4.330

5.  Commissural geometry and cusp fusion insights to guide bicuspid aortic valve repair.

Authors:  Jama Jahanyar; Gebrine El Khoury; Laurent de Kerchove
Journal:  JTCVS Tech       Date:  2021-01-29
  5 in total

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