BACKGROUND: As evidence is mounting regarding irrational and often unnecessary use of antibiotics during the COVID-19 pandemic a cross-sectional Point Prevalence Survey (PPS) (in accordance with WHO guideline) was conducted across COVID-19 dedicated wards in Dhaka Medical College and Hospital (DMCH). METHODOLOGY: Antibiotic usage data were collected from 193 patients at different COVID-19 dedicated wards at DMCH on 11 June 2020. Comparisons in antibiotic usage were made between different groups using Pearson chi-square and Fisher's exact test. RESULT: Findings reveal all surveyed patients (100%) were receiving at least one antibiotic with 133 patients (68.91%) receiving multiple antibiotics. Overall, patients presenting with the severe disease received more antibiotics. Third-generation cephalosporins (i.e. ceftriaxone) (53.8%), meropenem (40.9%), moxifloxacin (29.5%), and doxycycline (25.4%) were the four most prescribed antibiotics among surveyed patients. Diabetes mellitus (DM) was independently associated with multiple antibiotic prescribing. Abnormal C-reactive protein (CRP) and serum d-dimer were linked with higher odds of multiple antibiotic prescribing among study patients. CONCLUSION: Prevalence of multiple antibiotic prescriptions was high among severely ill patients and those with abnormal CRP and d-dimer levels. Data regarding the quality of antibiotic prescribing were lacking.
BACKGROUND: As evidence is mounting regarding irrational and often unnecessary use of antibiotics during the COVID-19 pandemic a cross-sectional Point Prevalence Survey (PPS) (in accordance with WHO guideline) was conducted across COVID-19 dedicated wards in Dhaka Medical College and Hospital (DMCH). METHODOLOGY: Antibiotic usage data were collected from 193 patients at different COVID-19 dedicated wards at DMCH on 11 June 2020. Comparisons in antibiotic usage were made between different groups using Pearson chi-square and Fisher's exact test. RESULT: Findings reveal all surveyed patients (100%) were receiving at least one antibiotic with 133 patients (68.91%) receiving multiple antibiotics. Overall, patients presenting with the severe disease received more antibiotics. Third-generation cephalosporins (i.e. ceftriaxone) (53.8%), meropenem (40.9%), moxifloxacin (29.5%), and doxycycline (25.4%) were the four most prescribed antibiotics among surveyed patients. Diabetes mellitus (DM) was independently associated with multiple antibiotic prescribing. Abnormal C-reactive protein (CRP) and serum d-dimer were linked with higher odds of multiple antibiotic prescribing among study patients. CONCLUSION: Prevalence of multiple antibiotic prescriptions was high among severely ill patients and those with abnormal CRP and d-dimer levels. Data regarding the quality of antibiotic prescribing were lacking.
Authors: Timothy M Rawson; Luke S P Moore; Nina Zhu; Nishanthy Ranganathan; Keira Skolimowska; Mark Gilchrist; Giovanni Satta; Graham Cooke; Alison Holmes Journal: Clin Infect Dis Date: 2020-12-03 Impact factor: 9.079
Authors: Dilip Nathwani; Jacqueline Sneddon; William Malcolm; Camilla Wiuff; Andrea Patton; Simon Hurding; Anne Eastaway; R Andrew Seaton; Emma Watson; Elizabeth Gillies; Peter Davey; Marion Bennie Journal: Int J Antimicrob Agents Date: 2011-04-22 Impact factor: 5.283
Authors: Waqas Ullah; Nishanth Thalambedu; Shujaul Haq; Rehan Saeed; Shristi Khanal; Shafaq Tariq; Sohaib Roomi; John Madara; Margot Boigon; Donald C Haas; David L Fischman Journal: J Community Hosp Intern Med Perspect Date: 2020-09-03
Authors: Sock Hoon Tan; Tat Ming Ng; Hui Lin Tay; Min Yi Yap; Shi Thong Heng; Audrey Yong Xin Loo; Christine B Teng; Tau Hong Lee Journal: J Glob Antimicrob Resist Date: 2020-12-08 Impact factor: 4.035
Authors: Kiran Ramzan; Sameen Shafiq; Iqra Raees; Zia Ul Mustafa; Muhammad Salman; Amer Hayat Khan; Johanna C Meyer; Brian Godman Journal: Antibiotics (Basel) Date: 2022-06-09
Authors: Zia Ul Mustafa; Muhammad Salman Saleem; Muhammad Nabeel Ikram; Muhammad Salman; Sanan Amjad Butt; Shehroze Khan; Brian Godman; R Andrew Seaton Journal: Pathog Glob Health Date: 2021-11-16 Impact factor: 3.735
Authors: Ibrahim Franklyn Kamara; Ajay M V Kumar; Anna Maruta; Bobson Derrick Fofanah; Charles Kuria Njuguna; Steven Shongwe; Francis Moses; Sia Morenike Tengbe; Joseph Sam Kanu; Sulaiman Lakoh; Alie H D Mansaray; Kalaiselvi Selvaraj; Mohammed Khogali; Rony Zachariah Journal: Int J Environ Res Public Health Date: 2022-03-28 Impact factor: 3.390