Literature DB >> 34312607

Granular cell tumor of the abdominal wall, a case report and review of literature.

Sarwat Rehan1, Hamza Paracha2, Rehan Masood3, Robby Wang4.   

Abstract

Granular cell tumors (GCTs) on the abdominal wall are rare and present as a painless superficial abdominal mass. We report the case of a 73-year-old female, who presented to the family medicine practice with a painless subcutaneous anterior abdominal wall mass. Ultrasound showed a 0.9×0.5×1.3 cm3 hyperechoic solid lesion with distal shadowing within the subcutaneous tissue of the anterior abdominal wall. The X-ray did not show any calcification within the subcutaneous tissue which ruled out metastatic calcified lesions. The patient was referred to general surgery for further evaluation. A previous computed tomography (CT) revealed a nonspecific 12 mm lesion involving the skin and subcutaneous fat in the right upper quadrant of the anterior abdominal wall. The lesion was excised under local anesthesia and sent for histopathological analysis. CD68 highlighted the multitude of macrophages microscopically. Histopathology demonstrated CKAE1/AE3 was negative for any epithelial components and S100 was diffusely positive. A final diagnosis of GCT was made. On follow-up, the patient underwent excision of the scar tissue with no evidence of atypia or GCT. This case is unique due to its benign presentation and limited reported literature. Further evaluation of a painless subcutaneous lesion is imperative to rule out rare conditions and the possibility of recurrent or metastatic malignancy. 2021 AME Case Reports. All rights reserved.

Entities:  

Keywords:  Granular cell tumor (GCT); case report; general surgery; myoblastoma; superficial abdominal mass

Year:  2021        PMID: 34312607      PMCID: PMC8256110          DOI: 10.21037/acr-20-160

Source DB:  PubMed          Journal:  AME Case Rep        ISSN: 2523-1995


  16 in total

1.  Mohs micrographic surgery for granular cell tumor using S-100 immunostain.

Authors:  Sidney B Smith; Mary F Farley; John G Albertini; Dirk M Elston
Journal:  Dermatol Surg       Date:  2002-11       Impact factor: 3.398

2.  Malignant granular cell tumor: Clinical features and long-term survival.

Authors:  Ambria S Moten; Huaqing Zhao; Hong Wu; Jeffrey M Farma
Journal:  J Surg Oncol       Date:  2018-09-09       Impact factor: 3.454

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Journal:  Ann Surg       Date:  1973-02       Impact factor: 12.969

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Journal:  Am J Clin Pathol       Date:  1969-08       Impact factor: 2.493

5.  Colorectal granular cell tumor: a clinicopathologic study of 26 cases.

Authors:  Aatur D Singhi; Elizabeth A Montgomery
Journal:  Am J Surg Pathol       Date:  2010-08       Impact factor: 6.394

Review 6.  Malignant granular cell tumor: report of a case and review of the literature.

Authors:  H Sonobe; J Iwata; M Furihata; T Moriki; Y Ohtsuki
Journal:  Pathol Res Pract       Date:  1998       Impact factor: 3.250

7.  Immunohistochemical localization of S-100 protein and peripheral nerve myelin proteins (P2 protein, P0 protein) in granular cell tumors.

Authors:  M Mukai
Journal:  Am J Pathol       Date:  1983-08       Impact factor: 4.307

8.  Granular cell tumor: a clinicopathologic study of 110 patients.

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Journal:  J Surg Oncol       Date:  1980       Impact factor: 3.454

9.  Malignant granular cell tumor of soft tissue: diagnostic criteria and clinicopathologic correlation.

Authors:  J C Fanburg-Smith; J M Meis-Kindblom; R Fante; L G Kindblom
Journal:  Am J Surg Pathol       Date:  1998-07       Impact factor: 6.394

10.  Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival.

Authors:  Yara A Alnashwan; Khaled A H Ali; Samir S Amr
Journal:  Case Rep Pathol       Date:  2019-04-07
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  1 in total

1.  Malignant granular cell tumor in the thoracic wall: A case report.

Authors:  Shengnan Gao; Bin Xing; Sun Lichao; Jie Luo; Jiao Tang; Ye Wang; Xiaoyan Zhang
Journal:  Front Oncol       Date:  2022-09-20       Impact factor: 5.738

  1 in total

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