Literature DB >> 34308466

GSH-resistant and highly cytoselective ruthenium(II)-p-cymene-(imidazo[4,5-f][1,10]phenanthrolin-2-yl)phenol complexes as potential anticancer agents.

Binoy Kar1, Utpal Das1, Sourav De1, Sudhindra Pete1, Ajay Sharma S1, Nilmadhab Roy1, Ashok Kumar S K1, Debashis Panda2, Priyankar Paira1.   

Abstract

To avoid the side effects of the current popular platinum-based anticancer drugs, researchers have made tireless attempts to design appropriate GSH-resistant Ru(ii)-arene complexes. In this regard, luminescent ruthenium(ii)-p-cymene-imidazophenanthroline complexes were developed as promising highly cytoselective cancer theraputic agents for HeLa and Caco-2 cells.

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Year:  2021        PMID: 34308466     DOI: 10.1039/d1dt01604k

Source DB:  PubMed          Journal:  Dalton Trans        ISSN: 1477-9226            Impact factor:   4.390


  1 in total

1.  Mitochondria-targeted half-sandwich iridium(iii)-Cp*-arylimidazophenanthroline complexes as antiproliferative and bioimaging agents against triple negative breast cancer cells MDA-MB-468.

Authors:  Ashaparna Mondal; Shanooja Shanavas; Utsav Sen; Utpal Das; Nilmadhab Roy; Bipasha Bose; Priyankar Paira
Journal:  RSC Adv       Date:  2022-04-19       Impact factor: 4.036

  1 in total

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