Literature DB >> 34304655

A comprehensive insight on the biological potential of embelin and its derivatives.

N Jeelan Basha1, S M Basavarajaiah2, Swathi Baskaran1, Prasanna Kumar1.   

Abstract

Naturally occurring bioactive molecules are known for their diverse biological applications such as antimicrobial, anticancer, anti-inflammatory, and analgesic activities. Also, some of the natural products act as medicinal drugs. Further, bioactive cell-permeable molecule embelin has been reported for its diverse biological activities such as antimalarial, anticancer, and anti-inflammatory in the literature. With the continuation of our research work on biologically active molecules, based on structural activity relationship and docking studies of embelin and its derivatives, we have reported target-specific anticancer and antimalarial activities of embelin and its analogs. Also, it has been reported in many recent research articles that embelin and its derivatives are known to possess medicinal properties. This review mainly highlights recent reports on broad-spectrum biological activities of the embelin and its analogs to date.

Entities:  

Keywords:  Embelin; anti-diabetic; anticancer; antimalarial; antimicrobial; antioxidant activity; antiviral

Mesh:

Substances:

Year:  2021        PMID: 34304655     DOI: 10.1080/14786419.2021.1955361

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  2 in total

1.  Synthesis, spectral analysis, DFT calculations, biological potential and molecular docking studies of indole appended pyrazolo-triazine.

Authors:  S M Basavarajaiah; G Y Nagesh; Mohammad Javeed; Rashmi Bhat; S Nethravathi; Jeelan N Basha; K Ramakrishna Reddy; C Nisarga; Pooja Srinivas
Journal:  Mol Divers       Date:  2022-05-10       Impact factor: 2.943

Review 2.  Therapeutic potential of pyrrole and pyrrolidine analogs: an update.

Authors:  N Jeelan Basha; S M Basavarajaiah; K Shyamsunder
Journal:  Mol Divers       Date:  2022-01-25       Impact factor: 3.364

  2 in total

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