Shuangshuang Yang 1 , Yunpeng Ba 1 , Guozhong Jiang 2 Show Affiliations »
Abstract
Objective:To explore the clinical features and prognosis of CD20-positive extranodal NK/T cell lymphoma. Methods: To analyze the clinical characteristics and prognosis of 11 ENKTL patients admitted to this hospital. Results: Among the 11 patients, 6 cases with elevated LDH, 6 cases of anemia, and 8 cases with Ki-67≥50%. Two cases survived; 1 case lost contact; 8 cases died, and the average survival time of 8 cases was 22.5 months. Conclusion: The diagnosis of CD20 positive ENKTL is difficult, which requires a combination pathomorphology, immunohistochemistry, EBER and gene rearrangement detection and improve the understanding of the disease.Early diagnosis and active treatment is important. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.
Objective:To explore the clinical features and prognosis of CD20 -positive extranodal NK/T cell lymphoma . Methods: To analyze the clinical characteristics and prognosis of 11 ENKTL patients admitted to this hospital. Results: Among the 11 patients , 6 cases with elevated LDH, 6 cases of anemia , and 8 cases with Ki-67≥50%. Two cases survived; 1 case lost contact; 8 cases died , and the average survival time of 8 cases was 22.5 months. Conclusion: The diagnosis of CD20 positive ENKTL is difficult, which requires a combination pathomorphology, immunohistochemistry, EBER and gene rearrangement detection and improve the understanding of the disease.Early diagnosis and active treatment is important. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.
Entities: Disease
Gene
Species
Keywords:
CD20; immunochemistry; nose neoplasms; pathology
Mesh： See more »
Year: 2021
PMID： 34304470 DOI： 10.13201/j.issn.2096-7993.2021.05.012
Source DB: PubMed Journal: Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi ISSN： 2096-7993